International publications




C. Lionis, A. Kafatos, J. Vlachonicolis, M. Vakaki, M. Tzortzi, A. Petraki. The effects of a health education intervention program among Cretan adolescents. Preventive Medicine 1991; 20:685


Y. Alamanos, K. Tsamandouraki, A. Koutis, C. Lionis, M. Fioretos. Obesity, Hypertension, Hypercholesterolemia and Diabetes Mellitus in Women Aged 20


Α. D. Koutis, A. Isacsson, L. H. Lindholm, C. D. Lionis, K. Svenninger, M. Fioretos. Use of primary health care in Spili, Crete, and in Dalby, Sweden. Scandinavian Journal of Primary Health Care 1991; 1991; 9:297-302.






Α. Isacsson, A. D. Koutis, M. Cedervall, L. H. Lindholm, C. D. Lionis, K. Svenninger, M. Fioretos. Patient-number-based computerized medical records in Crete. A tool for planning and assessment of primary health care. Computer Methods and Programs in Biomedicine 1992; 37:41-9.


L. H. Lindholm, A. D. Koutis, C. D. Lionis, I. G. Vlachonikolis, A. Isacsson, M. Fioretos. Risk factors for ischaemic heart disease in a Greek population. A cross-sectional study of men and women living in the village of Spili in Crete. European Heart Journal 1992; 13:291-8.


Α. D. Koutis, C. D. Lionis, A. Isacsson, A. Jakobsson, M. Fioretos, L. H. Lindholm. Characteristics of the "metabolic syndrome X" in a cardiovascular low risk population in Crete. European Heart Journal 1992; 13:865-71.






Α. D. Koutis, A. Isacsson, C. D. Lionis, L. H. Lindholm, K. Svenninger, M. Fioretos. Differences in the diagnose panorama in primary health care in Dalby, Sweden and Spili, Crete. Scandinavian Journal of Social Medicine 1993; 21:51-8.


L. H. Lindholm, S. Jern,C. D. Lionis, A. D. Koutis, A. Jakobsson, A. Isaksson, B. Slaug, M. Fioretos. Electrocardiographic signs of coronary heart disease in a "low risk" population in rural Crete. Coronary Artery Disease 1993; 4:427-35.


C. D. Lionis, A. D. Koutis, N. Antonakis, A. Isacsson, L. H. Lindholm, M. Fioretos. Mortality rates in a cardiovascular "low-risk" population in rural Crete. Family Practice 1993; 10:300-4.


M. Fioretos, K. Davidson, T. Faresjö, Y. Alamanos, A. Koutis, C. Lionis, E. Trell, K. Tsamandouraki. Hospital admission in two European landscapes - comparison between Heraklion, Greece and Linkoping, Sweden. International Journal of Health Sciences 1993; 4:33-40.






K. Tsamadouraki, Y. Alamanos, T. Faresjö, K. Davidson, A. Koutis, C. Lionis, E. Trell, M. Fioretos. Hospital admissions for different cancer diagnosis: a comparison between two European landscapes. Anticancer Research 1994; 14:2167-70.






C. D. Lionis, S. M. Sasarolis, A. D. Koutis, N. A. Antonakis, A. Benos, S. Papavasiliou, M. Fioretos. Measuring the prevalence of diabetes mellitus in a Greek primary health care district. Family Practice 1996; 13:18-21.


C. Lionis, E. Grassi, G. Bellos, C. Chiari. Doctor-patient communication in Mediterranean countries: The Reggio Emilia consensus. European Journal of General Practice 1996; 2:36- 7.


K. Davidson, E. Trell, C. Lionis, A. Koutis, T. Faresjö, T. Timpka, M. Fioretos. Following the thread of Ariadne to the health of women. Health Care for Women International 1996; 17:201-8.


C. Lionis and G. Frantzeskakis. Atrial fibrillation in a primary health care district in rural Crete. British Journal of General Practice 1996; 46:624.


T. Faresjö, C. Lionis, A. Koutis, M. Fioretos, E. Trell. Kan vi folja Ariadnes trad till en battre folkhalsa? Allmanmedicin 1996; 17:159-62.






C. Lionis, M. Koulentaki, E. Biziagos, E. Kouroumalis. Current prevalence of hepatitis A, B and C in a well-defined area in rural Crete, Greece. Journal of Viral Hepatitis 1997; 4:55-61.


Μ. Antoniou, C. Lionis, Y. Tselentis. A focus of Fasciolα hepatica in Crete without human cases. European Journal of Epidemiology 1997; 13:99-101.


K. Davidson, C. Lionis, T. Faresjö, A. Koutis, M. Fioretos, M. Foldevi, E. Trell. Differential cancer morbidity towards year 2000 in a population disease outlook across Europe I. The female gender. Anticancer Research 1997; 17:541-54.


C. Lionis, E. Frangoulis, M. Koulentakis, E. Biziagos, E. Kouroumalis. Prevalence of hepatitis A, B, and C markers in school children of a rural area of Crete, Greece. European Journal of Epidemiology 1997; 13:417-20.


M. Foldevi, C. Lionis, A. Koutis, M. Fioretos, T. Faresjö, E. Trell, K. Davidson. Differential cancer morbidity towards year 2000 in a population disease outlook across Europe II. The male gender. Anticancer Research 1997; 17:2707-13.






M. Chatziarsenis, C. Lionis, T. Faresjö, M. Fioretos, E. Trell. Community-based medical systems in a hospital-primary health care centre in Crete, Greece: concepts, methods, and the new role of the general practitioner. Journal of Medical Systems 1998; 22:173-88.


C. Lionis, M. Chatziarsenis, N. Antonakis, Y. Gianoulis, M. Fioretos.Assessment of vaccine coverage of school children in three primary health care areas in rural Crete, Greece. Family Practice 1998; 15:443-8.


C. Lionis, Å. Faresjö, T. Faresjö, M. Skoula, M. Kapsokefalou. Antioxidant effects of herbs in Crete. Lancet 1998; 352:1987-8.


E. A. Skliros, A. Sotiropoulos, C. Lionis, N. C. Tassopoulos. Hepatitis B and C virus infection in patients with high serum transaminases. Postgraduate Medical Journal 1998; 74:511.


C. Lionis.[Atención Primaria: towards a journal with Mediterranean and Southern Europe dimension]. Atención Primaria 1998; 22:617-8.






E. A.Skliros, A. Sotiropoulos, T. Peppas, K. Sofroniadou, C. Lionis. High prevalence of HBV infection markers in refugees from eastern countries. Italian Journal of Gastroenterology Hepatology 1999; 31:84-5.


C. Lionis, E. Frangoulis, S. Skliros, E. Alexandrakis, E. Kouroumalis. How Greek GPs manage hepatitis C infected patients: experiences gained from a primary health care district in rural Crete. Australian Journal of Family Physicians 1999; 28:207.


C. Lionis, T. Faresjö, A. Koutis, M. Fioretos, E. Trell. Unwinding Ariadne′s thread: some methodological and interpretative considerations on international hospital admission comparisons. Anticancer Research 1999; 19:1411-8.


M. Chatziarsenis, C. Lionis,E. Makri, K. Sapouna, M. Fioretos, T. Faresjö, M. Mavromanolakis, J. Vlachonikolis, E. Trell. Bringing community involvement into a Cretan primary/hospital care center: an evaluation of population habits and attitudes toward health care. Journal of Medical Systems 1999; 23:123-31.


C. Lionis and E. Trell. Health needs assessment in General Practice: The Cretan approach. European Journal of General Practice 1999; 5:75-7.


M. Chatziarsenis, S. Miyakis, T. Faresjö, M. Fioretos, J. Vlachonicolis, E. Trell, C. Lionis. Is there room for general practice in penitentiary institutions: screening and vaccinating high risk groups against hepatitis. Family Practice 1999; 16: 366-8.


L. Spång, E. A. Thireos, C. Lionis, E. Trell. Face and contents validity, and feasibility of Healthometer: a Delphi study. Journal of Medical System 1999; 23:457-65.





C. Lionis, I. G. Vlachonikolis, S. Skliros, A. Symeonidis, B. P. Merkouris, E. Kouroumalis. Do undefined sources of hepatitis C transmission exist? The Greek study in general practice. Journal Viral of Hepatitis 2000; 7:218-24.


I. Kristjansson, T. Faresjo, C. Lionis, A. R. Nosratabadi, K. Gudmundsson, A. Halling, C. Tagesson. Assessment of aluminium in human deciduous teeth. European Journal of Epidemiology 2000; 16:231-3.


P. Van Royen, F. Griffith, C. Lionis, J. Rethans, H. Sandholzer, F. Gali. A research strategy for EGPRW. European Journal of General Practice 2000; 6:69-71.


C. Lionis, I. Vlachonikolis, M. Bathianaki, G. Daskalopoulos, S. Anifantaki, A. Cranidis. Urinary incontinence, the hidden health problem of Cretan women: report from a primary care survey in Greece. Women and Health 2000; 31:59-66.


E. Mazokopakis, I. Vlachonikolis, A. Philalithis, C. Lionis. Seroprevalence of hepatitis A, B and C markers in Greek warship personnel. European Journal of Epidemiology 2000; 16:1069-72.


C. Lionis, S. Sasarolis, G. I. Kasotakis, G. M. Lapidakis, A. I. Stathopoulos. Investigation of accuracy of death certificate completion and implications on mortality statistics in Greece. European Journal of Epidemiology 2000; 16:1081.






S. Argyriadou, H. Melissopoulou, E. Krania, A. Karagiannidou, J. Vlachonikolis, C. Lionis.Dementia and depression: two frequent disorders of the aged in primary health care in Greece. Family Practice 2001; 18:87-91.


C. Lionis and N. Antonakis. Theses written by GP's are increasing in Greece. European Journal of General Practice 2001; 7:35-6.


D. Glaros, C. Lionis, H. Qiqi, P. Theodorakis, E. Trell. Healthcare in Albania; what of the future? Lancet 2001; 357: 1047.


M. Chatziarsenis, E. Makri, K. Sapouna-Chatziarseni, M. Fioretos, T. Faresjö, E. Trell, C. Lionis. Care preferences in a Cretan community with integrated hospital/general practice services. International Journal of Health Care Quality Assurance 2001; 14:189-92.


D. Drygiannakis, C. Lionis, I. Drygiannakis, G. Pappas, E. Kouroumalis. Low prevalence of liver - kidney microsomal autoantibodies of type 1 (LKM1) in hepatitis C seropositive subjects on Crete, Greece. BioMed Central Gastroenterology 2001; 1:4.


P. N. Theodorakis, L. Rrumbullaku, D. Glaros,C. Lionis,E. Trell. ["Green islands" for for primary health care in the Balkan?]. Lakartidnigen 2001; 98:2747.


J. Gillies, C. Lionis, J. MacDonald, C. Laird, J. Szabo, B. Nunes, L. Burriel, H. Lund, C. Made. Dealing with emergencies in rural areas of Europe: proceedings from WONCA Europe 2000. Emergency Medicine Journal 2001; 18:305-7.


S. Skliros, C. Lionis,L. Foudoulaki, A. Sotiropoulos, E. Kouroumalis, D. Spandidos. Hepatitis B and C markers in a Kurdish refugees camp in Greece. Journal of Gastroenterology and Hepatology 2001; 16:839-40.


C. Lionis, M. Tzagournissakis, E. Iatraki, M. Kozyraki, N. Antonakis, A. Plaitakis. Are primary care physicians able to assess dementia? An estimation of their capacity after a short-term training program in rural Crete. American Journal of Geriatric Psychiatry 2001; 9:3.


E. Rovithis, C. Lionis, S. Schiza, D. Bouros, A. Karokis, Ι. Vlachonikolis, N. Siafakas. Assessing the knowledge of bronchial asthma among primary health care physicians in Crete: A pre- and post-test following an educational course. BioMed Central Medical Education 2001; 1:2.


C. Lionis, M. Bathianaki, N. Antonakis, S. Papavasiliou, A. Philalithis.A high prevalence of diabetes mellitus in a municipality of rural Crete, Greece. Some results from a primary care study. Diabetic Medicine 2001; 18:1-2.


S. Argyriadou, I. Vlachonikolis, H. Melisopoulou, K. Katachanakis, C. Lionis. In what extent anemia coexists with cognitive impairment in elderly: a cross-sectional study in Greece. BioMed Central Family Practice 2001; 2:5.


A. Evangeliou, C. Lionis, H. Michailidou, M. Spilioti, A. Kanitsakis, E. Balomenaki, P. Nikitakis, N. Drakonakis, C. Giannakopoulou, S. Sbyrakis. Selective screening for inborn errors of metabolism: the primary care based model in rural Crete. Journal of Inherited Metabolic Disease 2001; 24:877-80.


C. Lionis, I. Vlachonikolis, M. Chatziarsenis, T. Faresjö, I. Kristjansson, M. Tzagournisakis, A. Plaitakis, E. Trell. Managing Alzheimer's disease in primary care in Crete, Greece: room for improvement. Quality Management in Health Care 2001; 9:16-21.






L. Rrumbullaku, P. N Theodorakis, P. Caca, C. Lionis, E. Trell. Medical education in Albania: current situation and perspective with reference to primary care. Croatian Medical Journal 2002; 43:50-3.


P. Malferheiner, F. Mégraud, C. O′Morain, A. P. Hungin, R. Jones, A. Axon, D. Y. Graham, G. Tytgat, The European Helicobacter Pylori Study Group (EHPSG). Current concepts in the management of Helicobacter pylori infection – The Maastricht 2 – 2000. Consensus Report. Alimentary Pharmacology and Therapeutics 2002; 16:167-80.


C. Lionis, K. Ereunidou, N. Antonakis, S. Argyriadou, I. Vlachonicolis, A. Katsamouris. Chronic venous insufficiency - a common health problem in general practice in Greece. International Angiology 2002; 21:86-92.


D. P. Tsagaraki, A. E. Evangeliou, M. Tsilimbaris, M. G. Spilioti, E. P. Mihailidou, C. Lionis, I. Pallikaris. The significance of ophthalmologic evaluation in the early diagnosis of inborn errors of metabolism: the Cretan experience. BioMed Central Ophthalmology 2002; 2:2.


E. A. Skliros, I. Papaioannou, A. Sotiropoulos, G. Giannakaki, M. Milingou, C. Lionis. A high level of awareness but a poor control of hypertension among elderly Greeks. The Nemea primary care study. Journal of Human Hypertension 2002; 16: 285-7.


E. E. Mazokopakis and C. D. Lionis. Epidemiology of injuries aboard a Greek warship. Military Medicine 2002; 167:xi.


L. Rrumbullaku, P. Theodorakis, P. Pullugi, C. Lionis, E. Trell. Postgraduate training in family medicine in Albania. Postgraduate Medical Journal 2002; 78:308-10.


J. K. Soler, C. Lionis, M. Kaloeidas, S. Skliros, E. Drosos, G. Almagor, B. Bisharat, E. Kitai, D. Tayar, J. Mendive, L. Pisco, F. Carelli, M. Ungan. Developing a Mediterranean family medicine group: The Malta consensus. European Journal of General Practice 2002; 8:69-70.


E. Mazokopakis, J. Vlachonikolis, M. Sgantzos, I. Polychronidis, V. Mavreas, C. Lionis. Mental Distress and Socio-Demographic Variables. A study of Greek warship personnel. Military Medicine 2002; 167:883-8.


C. Lionis. Epidemiology and general practice: an unbroken link. Attention Primaria 2002; 30:573-5. (Editorial).


A. Evangeliou, E. Dafnis, C. Perdikoyanni, M. Spilioti, C. Lionis, M. Kalmanti. Hematological abnormalities in inborn errors of metabolism – how frequent are they? The Cretan experience. European Journal of Pediatric Hematology 2002; 19:581-5.






D. Kounalakis, C. Lionis, I. Okkes, H. Lamberts. Developing an appropriate EPR system for the Greek primary care setting. Journal of Medical Systems 2003; 27:239-46.


E. Mazokopakis, E. Ganotakis, C. Lionis.The Greek armed forces are vulnerable to HAV infection. Military Medicine 2003; 168:v.


D. Sapountzi-Krepia, N. Antonakis, M. Sgantzos, C. Lionis.  Seeking the attitudes and perceptions of the Greek primary-care professionals on voluntary work in caring for people with HIV/AIDS. Journal of Nursing Management 2003; 11:258-65.


E. Mazokopakis and C. Lionis.Substance use and mental health in Greek warship personnel. Military Medicine 2003; 168:ix-x.


Ε. Mazokopakis, I. Vlachonicolis, C. Lionis.Smoking behavior of Greek warship personnel. Military Medicine 2003; 168:929-33.


G. Mantzavinis, P. N. Theodorakis, C. Lionis, E. Trell. [Geographical inequalities in the distrubition of general practitioners in Sweden]. Lakartidningen 2003; 100:4294-7.


C. D. Lionis, P. S. Worley. Emergence of the European section of the International Journal of Rural and Remote Health. Rural and Remote Health 2003; 3:257.






C. Lionis, M. Antonopoulou, K. Volitaki, E. Thireos. Coronary risk assessment of university students with premature parental coronary heart disease. Journal of American College Health 2004; 52:237-8.


M. Antonopoulou, C. Ekdahl, M. Sgantzos, N. Antonakis, C. Lionis.Translation and standardization into Greek of the standardized general Nordic questionnaire for the musculoskeletal symptoms. The European Journal of General Practice 2004; 10:33-4.


G. Liangas and C. Lionis. General Practice in Greece: a student’s and supervisor’s perspective. Australian Journal of Rural Health 2004; 12:112-4.


C. Lionis, F. Carelli, J. K. Soler. Developing academic career in family medicine within the Mediterranean setting. Family Practice 2004; 21:477-8. (Editorial).


C. Lionis, H. E. Stoffers, E. Hummers-Pradier, F. Griffiths, D. Rotar-Pavlic, J. J. Rethans. Setting priorities and identifying barriers in research for general practice in Europe. Results from an EGPRW meeting. Family Practice 2004; 21:587-93.


C. Lionis, M. Tsiraki, V. Bardis, A. Philalithis. Seeking quality improvement in primary care in Crete, Greece: the first actions. Croatian Medical Journal 2004; 45:599-603.


T. Zachariadou, D. Floridou, E. Angelidou, A. Philalithis, C. Lionis. Diagnoses panorama in the primary healthcare setting in Cyprus. Data from a pilot study. European Journal of General Practice 2004; 10:102-3.


A. Mariolis, B. Merkouris, C. Lionis. Introducing general practice in urban Greece: focus on morbidity. European Journal of General Practice 2004; 10:105-6.


E. Mazokopakis, J. Papadakis, M. Papadomanolaki, G. Vrentzos, E. Ganotakis, C. Lionis. Overweight and obesity in Greek warship personnel: prevalence and correlations. European Journal of Public Health 2004; 14:395-7.


K. Souliotis and C. Lionis.Creating an integrated health care system in Greece: a primary care perspective. Journal of Medical Systems 2004; 28:643-52.


K. Erevnidou, R. Launois, A. Katsamouris, C. Lionis.Translation and validation of a quality of life questionnaire for chronic lower limp venous insufficiency into Greek. International Angiology 2004; 23:394-9.






L. Chatzi, E. Prokopakis, N. Tzanakis, A. Alegakis, I. Bizakis, N. Siafakas,C. Lionis.Allergic rhinitis, asthma, and atopy among grape farmers in a rural population in Crete, Greece. Chest 2005; 127:372-8.


C.  Brotons, C. Björkelund, M. Bulc, R. Ciurana, M. Godycki-Cwirko, E. Jurgova, P. Kloppe, C. Lionis, A. Mierzecki, R. Piñeiro, L. Pullerits, M. R. Sammut, M. Sheehan, R. Tataradze, E. A. Thireos, J. Vuchak. EUROPREV network.Prevention and health promotion in clinical practice: the views of general practitioners in Europe. Preventive Medicine 2005; 40:595-601.


C. Lionis,G. Samoutis, C. Kouroussis, M. Trigoni, V. Georgoulias. Teaching cancer management to primary care staff: the first experiences gained from Crete. Journal of Cancer Education 2005; 20:6-7.


G. Belos, C. Lionis, M. Fioretos, J. Vlachonikolis, A. Philalithis. Clinical undergraduate training and assessment in primary care: experiences gained from Crete, Greece. BioMed Central Medical Education 2005; 5:13.


V. Vivilaki, A. Romanidou, P. Theodorakis, C. Lionis.Are health education meetings effective in recruiting women in cervical screening programmes? An innovative and inexpensive intervention from the island of Crete. Rural and Remote Health 2005; 5:376.


R. Pineiro, C. Brotons, M. Bulk, R. Ciurana, T. Drenthen, D. Durrer, M. Godycki-Cwirko, S. Gorpelioglu, P. Kloppe, C. Lionis, M. Mancini, C. Martis, A. Mierzecki, I. Pichler, L. Pullerits, M. R. Sammut, D. Sghedoni, M. Sheehan, E. A. Thireos. Healthy diet in primary care: views of general practitioners and nurses from Europe. European Journal of Clinical Nutrition 2005; 59 (Suppl1): S77-80.


C. Lionis,N. Dagdeviren, B. P. Merkouris, A. Caylan, A. Symeonidis, P. Topsever, A. Karotsis, A. Batikas, M. Ungan. Greek-Turkish collaboration in general practice/family medicine: An example of country-to-country collaboration. European Journal of General Practice 2005; 11:131-2.


D. M. Bushnell, M. L. Martin, K. H. Summers, J. Svihra, C. Lionis, L. Patrick. Quality of life of women with urinary incontinence: Cross-cultural performance of 15 language versions of the I-QOL. Quality of Life Research 2005; 14:1901-13.


C. Lionis,A. Olsen–Faresjo, F. Anastasiou, M. Wallander, S. Johansonn, T. Faresjo. Measuring the frequency of functional gastrointestinal disorders in rural Crete: a need for improving primary care physicians′ diagnostic skills. Rural and Remote Health 2005; 5:409.






L. Chatzi, A. Alegakis, S. Kruger-Krasagakis, C. Lionis. Skin symptoms and work-related skin symptoms among grape farmers in Crete, Greece. Americal Journal of Industrial Medicine 2006; 49:77-84.


A. Markaki, N. Antonakis, A. Philalithis, C. Lionis. Primary health care nursing staff in Crete: an emerging profile. International Nursing Review 2006; 53:16-8.


C. Lionis, E. Thireos, M. Antonopoulou, E. Rovithis, A. Philalithis, E. Trell. Assessing university students' health needs: lessons learnt from Crete, Greece. European Journal of Public Health 2006; 16:112.


T. Zachariadou, L. Makri, H. E. Stoffers, A. Philalithis, C. Lionis. The need for quality management in primary health care in Cyprus: results from a medical audit for patients with type 2 diabetes mellitus. Quality Management in Health Care 2006; 15:58-65.


N. Antonakis, I. Xylouri, M. Alexandrakis, C. Cavoura, C. Lionis. Seeking prescribing patterns in rural Crete: a pharmacoepidemiological study from a primary care area. Rural and Remote Health 2006; 6:488.


P. N. Theodorakis, G. D. Mantzavinis, L. Rrumbullaku, C. Lionis, E. Trell. Measuring health inequalities in Albania: a focus on the distribution of general practitioners. Human Resources for Health 2006; 4:5.


F. Anastasiou, N. Antonakis, G. Chaireti, P. N. Theodorakis, C. Lionis. Identifying dyspepsia in the Greek population: translation and validation of a questionnaire. BioMed Central Public Health 2006; 6:56.


Å. Faresjö, F. Anastasiou, C. Lionis, S. Johansson, M. A. Wallander, T. Faresjö. Health-related quality of life of irritable bowel syndrome in different cultural settings. Health and Quality of Life Outcomes 2006; 4:21.






L. Chatzi, A. Alegakis, N. Tzanakis, N. Siafakas, M. Kogevinas, C. Lionis. Association of allergic rhinitis with pesticides among grape farmers in Crete, Greece. Occupational and Environmental Medicine 2007; 64:417-21.


C. Lionis and J. Wynn-Jones. Establishing academic rural practice: a future and challenging target. Rural and Remote Health 2007; 7:727.


A. Markaki, N. Antonakis, C. M. Hicks, C. Lionis. Translating and validating a training needs assessment tool into Greek. BioMed Central Health Services Research 2007; 7:65.


M. Antonopoulou, N. Antonakis, A. Hadjipavlou, C. Lionis. Patterns of pain and consulting behaviour in patients with musculoskeletal disorders in rural Crete, Greece. Family Practice 2007; 24:209-16.


C. Lionis. Colorectal cancer screening and the challenging role of general practitioner/family physician: an issue of quality. Quality in Primary Care 2007; 15:129-31. (Editorial).


D. Panagiotakos, C. Lionis, A. Zeimbekis, V. Bountziouka, K. Makri, M. Economou, I. Vlachou, M. Micheli, N. Tsakountakis, G. Metallinos, E. Polychronopoulos. Long–term, moderate coffee consumption is associated with lower prevalence of diabetes mellitus among elderly non–tea drinkers from the Mediterranean islands (MEDIS Study). The Review of Diabetic Studies 2007; 4:105-11.


T. Abu-Mourad, S. Shashaa, A. Markaki, A. Alegakis, C. Lionis, A. Philalithis. An evaluation of patients′ opinions of Primary care Physicians of EUROPEP in Gaza Strip-Palestine. Journal of Medical Systems 2007; 31:497-503.


I. K. Karalis, A. K. Alegakis, A. G. Kafatos, A. D. Koutis, P. E. Vardas, C. D. Lionis. Risk factors for ischaemic heart disease in a Cretan rural population: a twelve year follow-up study. BioMed Central Public Health 2007; 7:351.


G. Samoutis, E. S. Soteriades, D. Kounalakis, T. Zachariadou, A. Philalithis, C. Lionis. Implementation of an electronic medical record system in previously computer naïve primary care centres: a pilot study from Cyprus. Informatics in Primary Care 2007; 15: 207-16.


A. Lamprakis, K. Vlassis, E. Siampou, I. Grammatikopoulos, C. Lionis. Can elbow extension test be used as an alternative to radiographs in primary care? European Journal of General Practice 2007; 13:221-4.


E. K. Symvoulakis, D. E. Kyrmizakis, E. I. Drivas, J. Bizakis, G. A. Velegrakis,C. Lionis.Angiotensin-converting enzyme inhibitor (ACE-I)- and angiotensin receptor blocker (ARB)-related angioedema: A neglected issue in daily practice in Greece. European Journal General Practice 2007; 13:239-41.


T. Abu-Mourad, S. Shashaa, A. Alegakis, C. Lionis, A. Philalithis. Translating and validating an instrument for measuring patients’ satisfaction with primary care physicians in Palestine: The case of EUROPEP. European Journal of General Practice 2007; 13:241-3.


J. K. Soler, F. Carelli, C. Lionis, H. Yaman. The wind of change: After the European definition-orienting undergraduate medical education towards general practice/family medicine. European Journal of General Practice 2007; 13:248-51.


A. Papathanasiou, I. Lentzas, E. Papavasiliou, C. Lionis. Chronic kidney disease among diabetic patients in a primary care setting, in rural Greece. Primary Care Diabetes 2007; 4:225.






T. Abu-Mourad, S. Radi, S. Shashaa,C. Lionis,A. Philalithis. Palestinian primary health care in light of the National Strategic Health Plan 1999-2003. Public Health 2008; 122:125-39.


J. Wilkinson, L. Berghmans, F. Imbert, B. Ledesert, A. Ochoa, the members of the ISARE II project team. Health indicators in the Europe regions-ISARE II. European Journal of Public Health 2008; 18:178-83.


B. Seifert, G. Rubin, N. De Wit, C. Lionis, N. Hall, P. Hungin, R. Jones, M. Palka, J. Mendive. The management of common gastrointestinal disorders in general practice. A survey by the European Society for Primary Care Gastroenterology (ESPCG) in six European countries. Digestive and Liver Disease 2008; 40:659-66.


G. Ivbijaro, L. Kolkiewicz, C. Lionis, I. Svab, A. Cohen, N. Sartorius. Primary care mental health and Alma-Ata. From evidence to action. Journal of Mental Health in Family Medicine 2008; 5:67-9.


A. Papathanasiou, S. Shea, A. Koutsovassilis, A. Melidonis, S. Papavasiliou, C. Lionis. Reporting distress and quality of life of patients with diabetes mellitus in primary and secondary care in Greece. Mental Health in Family Medicine 2008; 5:85-93.


T. Abu-Mourad, A. Alegakis, S. Shashaa, A. Koutis, C. Lionis, A. Philalithis. Individual determinants of primary health care utilization in Gaza Strip-Palestine. Journal of Epidemiology and Community Health 2008; 8:701-7.


J. K. Soler, H. Yaman, M. Esteva, F. Dobbs, R. D. Asenova, M. Katic, Z. Ozvacic, J. Pierre, A. Moreau, C. Lionis, P. Kotanyi, F. Carelli, P. Nowak, Z. Azeredo, E. Marklund, D. Chutchill, M. Ungan. Burnout in European family doctors: The EGPRN study. Family Practice 2008; 25: 245-65.


T. Zachariadou, H. E. Stoffers, C. A. Christophi, A. Philalithis,C. Lionis.Implementing the European guidelines for cardiovascular disease prevention in the primary care setting in Cyprus: lessons learned from a health care services study. BioMed Central Health Services Research 2008; 8:148.


M. Trouli, H. Vernon, K. Kakavelakis, M. Antonopoulou, A. Paganas, C. Lionis.Translation of the Neck Disability Index and validation of the Greek version in a sample of neck pain patients. BioMed Central Musculoskeletal Disorders 2008; 9:106.


C. Lionis and A. Papathanassiou. Primary care diabetes in Greece. Primary Care Diabetes 2008; 2:97-9.


D. Panagiotakos, C. Lionis,F. Anastasiou, A. Zeimbekis, E. Lioliou, I. Tsiligiani, S. Papoutsou, K. Vlysmas, G. Metallinos, E. Polychronopoulos. Prevalence of risk factors for cardiovascular disease by socio-economic status among the elderly from mediterranean islands: The MEDIS study. CVD Prevention and Control 2008; 3:153-62.


W. Qidwai, J. W. Beasley, F. J. Gomez-Clavelina, A. Abyad, T. Aziz, I. Bensenor, A. Biderman, A. Biscaia, M. A. Butt, J. A. Dickinson, M. F. Dikici, T. Edirne, P. Ferrinho, S. T. Go, P. Heinzelmann, C. Hogan, V. Inem, C. L. K. Lam, C. Lionis, M. Maier, D. P. Manca, P. R. Modi, M. F. Allam, M. N. Nangami, A. E. Nugmanova, M. O’Beirne, P. N. Orotta, R. Qureshi, S. Pessach, H. Smith, S. Sunwoo, M. Ungan, W. Cayley, H. Yaman, F. Yaris. The present status and future role of family doctors: a perspective from an international collaboration. Journal of Primary Health care, Research and Development 2008; 9:172-82.


A. Markaki and C. Lionis.Capacity building within primary healthcare nursing: a current European challenge. Quality in Primary Care 2008; 16:141-3 (Editorial).


G. Samoutis, E. Soteriades, H. Stoffers, T. Zachariadou, A. Philalithis, C. Lionis. Designing a multifaceted quality improvement intervention in primary care in a country where general practice is seeking recognition: the case of Cyprus. BioMed Central Health Services Research 2008; 8:181.


E. Symvoulakis, S. Klinis, I. Peteinarakis, D. Kounalakis, N. Antonakis, E. Tsafantakis, C. Lionis.Diagnosing a popliteal venous aneurysm in a primary care setting: A case report. Journal of Medical Case Reports 2008; 2:307.


C. Lionis and A. Philalithis. Patient satisfaction with medication: a challenge for primary health care. Family Practice 2008; 25:319-20.


C. Lionis, J. Allen, V. Sapouna, A. Alegakis, I. Svab. Towards the establishment of a new strategy for WONCA Europe: a key informants study. European Journal of General Practice 2008; 14:76-82.


M. Trigoni, F. Griffiths, D. Tsiftsis, E. Koumantakis, E. Green, C. Lionis. Mammography screening: views from women and primary care physicians in Crete. BioMed Central Women and Health Journal 2008; 3:127.


C. Kotsoni, A. Markaki, N. Antonakis, C. Lionis. Do patients with chronic obstructive pulmonary disease receive smoking cessation advice and interventions in rural Crete? Report from a medical audit study. Australian Journal of Rural Health 2008; 16:385-6.


F. Anastasiou, I. Mouzas, J. Moschandreas, E. Kouroumalis, C. Lionis.Exploring the agreement between diagnostic criteria for IBS in primary care in Greece. BioMed Central Research Notes 2008; 1:127.






S. Tyrovolas, E. Polychronopoulos, V. Bountziouka, A. Zeimbekis, I. Tsiligiani,    S. Papoutsou, E. Gotsis, C. Lionis, D. Panagiotakos. Level of adherence to the Mediterranean diet among elderly individuals living in Mediterranean Islands: nutritional report from the MEDIS study. Ecology of Food and Nutrition 2009; 48:76-87.


I. Lentzas, P. Papagiannopoulos, I. Nikolaidis, V. Garmiri, D. Vatides, A. Papathanasiou, A. Melidonis, G. Tsiros, P. Voila, C. Lionis. Idiopathic autoimmune hemolytic anemia due to lecithin overdose: a case report.  Cases Journal 2009; 2:97.


E. Germeni, C. Lionis, B. Davou, E. Petridou. Understanding reasons for poor motorcycle helmet use law compliance among eligible adolescent drivers in Greece. Journal of Injury Prevention 2009; 15:19-23.


D. B. Panagiotakos, C. Lionis, A. Zeimbekis,  K. Gelastopoulou, N. Papairakleous, Das UN, E. Polychronopoulos. Long-term tea intake is associated with reduced prevalence of (type 2) diabetes mellitus among elderly people from Mediterranean islands: MEDIS epidemiological study. Yonsei Medical Journal 2009; 50:31-8.


S. Tyrovolas, C. Lionis, A. Zeibekis, S. Bountziouka, M. Micheli, A. Katsarou, N. Pairakleous, G. Metallinos, K. Makri, E. Polychronopoulos, D. B. Panagiotakos. Increased body mass and depressive symptomatology are associated with hypercholesterolemia, among elderly individuals; results from the MEDIS study. Lipids in Health and Disease 2009; 8:10.


A. Markaki, A. Alegakis, N. Antonakis, A. Kalokerinou-Anagnostopoulou, C. Lionis. Exploring training needs of nursing staff in rural Cretan primary care settings. Applied Nursing Research 2009; 22:138-43.


M. Trigoni, M. Mahoney, J. Moschandreas, A. Markaki, C. Lionis. Cancer Control Practices: Translation and Cultural Adaptation of an Instrument in Crete, Greece. Journal of Cancer Education 2009; 24:105-6.


G. Kourlaba, E. Polychronopoulos, A. Zampelas, C. Lionis,D. Panagiotakos.  Development of a diet index for the elderly and it’s relation to cardiovascular disease risk factors; The elderly dietary Index. Journal American Diet Association 2009; 109:1022-30.


S. Tyrovolas, V. Bountziouka, N. Papairakleous, A. Zeimbekis, F. Anastasiou, E. Gotsis, G. Metallinos, E. Polychronopoulos, C. Lionis, D. Panagiotakos. Adherence to the Mediterranean diet is associated with lower prevalence of obesity among elderly people in Mediterranean islands: the MEDIS Study. International Journal of Food Sciences and Nutrition 2009; 11:1-14.


S. Tyrovolas, A. Zeimbekis, V. Bountziouka, K. Voutsa, G. Pounis, S. Papoutsou, G. Metallinos, E. Ladoukaki, E. Polychronopoulos, C. Lionis, D. Panagiotakos. Factors Associated with the Prevalence of Diabetes Mellitus Among Eldery Men and Woman Living in Mediterranean Islands: The MEDIS Study. The Review of Diabetic Studies 2009; 6:54-63.


V. Bountziouka, E. Polychronopoulos, A. Zeimbekis, E. Papavenetiou, E. Ladoukaki, N. Papairakleous, E. Gotsis, G. Metallinos, C. Lionis, D. Panagiotakos. Long-Term Fish Intake Is Associated With Less Severe Depressive Symptoms Among Elderly Men and Women: The MEDIS (MEDiterranean ISlands Elderly) Epidemiological Study. Journal of Aging Health 2009; 21: 864-80.


T. Faresjo, I. Karalis, E. Prinsback, K. Kroon, C. Lionis. Sense of coherence in Crete and Sweden: key findings and messages from a comparative study. European Journal of General Practice 2009; 15:95-8.


J. R. Wilkinson, L. Berghmans, F. Impert, B. Ledesert, A. Ochoa, G. Badeyan,  J. M. Berguristain-Aranzasti,  L. Berghmans, H. Brand, J. Brozova, N. Calleja, R. Dovicovic, D. Dupre, D. Fontaine, R. Gisser, P. Gorynki, W. Helmeier, S.  Holland, F. Imbert, S. Kardasis, S. Koskinen, C. Kaposvari,  J. Karashkevica, I. Karaskevics, D. Kounalakis, P. Kramers,  I. Larranga-Padilla, B. Ledérsert, C. Lionis, T. McCarthy, H. McGee, A. Montserrat, P. Muller, R. P. Asciak, A. Pathy, S. Pelaseyed, A. Pitard, N. Rasmussen, M. Roulleaux,  M. Ruuge, F. Sicard, G. Solomita, F. Tavares, A. Trugeon, W. Yared, H. van Veldhuizen, G. Weber, J. Wilkinson, L. Zwakhals. Health indicators in the European regions: expanding regional comparisons to the new countries of the European Union - ISARE III. Public Health 2009; 123:490-5.


V. G. Vivilaki, V. Dafermos, M. Kogevinas, P. Bitsios, C. Lionis. The Edinburg Postnatal Depression Scale: translation and validation for a Greek sample. BioMed Central Public Health 2009; 9:329.


C. Lionis, E. Symvoulakis, A. Markaki, C. Vardavas, M. Papadakaki, N. Daniilidou, K. Souliotis, I. Kyriopoylos. Integrated primary health care in Greece, a missing issue in the current health policy agenda: a systematic review. International Journal of Integrated Care 2009; 9:e88.


S. Anifantaki,   T. M. Filiz, A. Alegakis, P. Topsever, A. Markaki, N. D. Cinar, F. Sofras, C. Lionis. Does urinary incontinence affect quality of life of Greek women less severely? A cross-sectional study in two Mediterranean settings. Quality of Life Research 2009; 18:1311-9.


M. Antonopoulou, A. Alegakis, A. Hadjipavlou, C. Lionis. Studying the association between musculoskeletal disorders, quality of life and mental health. A primary care pilot study in rural Crete, Greece. BioMed Central Musculoskeletal Disorders 2009; 10:143.


E. Symvoulakis and C. Lionis. Hypertension and Compliance to Treatment in the Primary Care Setting: Key Issues from the Literature Review. Current Hypertension Reviews 2009; 5:307- 12.


S. Argyriadou and C. Lionis. Research in Primary care mental health in Greece. Mental Health in Family Medicine 2009; 6: 229-31.


D. R. Pavlic, P. de Graaf, F. Buntinx, C. Lionis. Primary care and care for chronic cancer patients in Europe: position paper of the European Forum for Primary Care. Quality Primary Care 2009; 17:431-43.


E. Hummers-Pradier, M. Beyer, P. Chevallier, S. Eilat-Tsanani, C. Lionis, L. Peremans, D. Petek, I. Rurik, J. K. Soler, H. E. Stoffers, P. Topsever, M. Ungan, P. Van Royen. The research agenda for general practice/family medicine and primary health care in Europe. Part 1. Background and methodology. European Journal of General Practice 2009; 15:243-50.


I. G. Tsiligianni, T. K. Vassilopoulos, P. K. Papadokostakis, G. K. Arseni, E. Astrinaki, C. D. Lionis. A two cases clinical report of mandragora poisoning in primary care in Crete, Greece: two case report. Cases Journal 2009; 2:9331.






C. Lionis, E. Symvoulakis, K. Vardavas. Implementing family practice research in countries with limited resources and capacity: A stepwise model experienced in Crete, Greece. Family Practice 2010; 27:48-54.


M. Helidoni, T. Nurry, J. Moshandreas, C. Lionis, A. Printza, G. Velegrakis. Cross-Cultural adaptation and validation of the voice handicap in index into Greek. Journal of Voice 2010; 24: 221-7.


E. Tourlouki, E. Polychronopoulos, A. Zeimbekis, N. Tsakountakis, V. Bountziouka, E. Lioliou, E. Papavenetiou, A. Polystipioti, G. Metallinos, S. Tyrovolas, E. Gotsis, A. L. Matalas, C. Lionis, D. B. Panagiotakos. The “secrets” of the long-livers in Mediterranean islands: the MEDIS study. European Journal of Public Health2010; 20:659-64.


I. A. Grammatikopoulos, G. Sinoff, A. Alegakis, D. Kounalakis, M. Antonοpoulou, C. Lionis. The Short Anxiety Screening Test in Greek: translation and validation. Annals of General Psychiatry 2010; 9:1.


E. Hummers-Pradier, M. Beyer, P. Chevallier, S. Eilat-Tsanani, C. Lionis, L. Peremans, D. Petek, I. Rurik, J. K. Soler, H. E. Stoffers, P. Topsever, M. Ungan, P. V.  Royen. Series: The research agenda for general practice/family medicine and primary health care in Europe. Part 2. Results: Primary care management and community orientation. European Journal of General Practice 2010; 16:42-50.


K. J. Gorter, J. Wens, K. Khunti, X. C. Claramunt, P. Topsever, T. Drivsholm, A. K. Jenum, C. Berkhout, M. Khalangot, M. Goldfracht, I. Rurik, C. Lionis, G. E. Rutten. The European EUCCLID pilot study on care and complications in an unselected sample of people with type 2 diabetes in primary care. Primary Care Diabetes 2010; 4:17-23.


C. I. Vardavas, E. K. Symvoulakis, G. Connolly, E. Patelarou, C. Lionis. What defines an effective anti-tobacco TV advertisement? A pilot study among Greek adolescents. International Journal of Environment Research and Public Health 2010; 7:78-88.


E. Polychronopoulos, G. Pounis, V. Bountziouka, A. Zeimbekis, I. Tsiligianni, B. E. Qira, E. Gotsis, G. Metallinos, C. Lionis, D. Panagiotakos. Dietary meat fats and burden of cardiovascular disease risk factors, in the elderly: a report from the MEDIS study. Lipids in Health and Disease 2010; 9:30. 


V. Vivilaki, V. Dafermos, M. Daglas, E. Antoniou, N. Tsopelas, P. Theodorakis, J. B. Browm, C. Lionis. Identifying intimate partner violence (IPV) during the postpartum period in a Greek sample.  Archives of Women’s Mental Health 2010; 13:467-76.


G. A. Samoutis, E. S. Soteriades, H. E. Stoffers, A. Philalithis, E. M. Delicha, C. Lionis. A pilot quality improvement intervention in patients with diabetes and hypertension in primary care settings of Cyprus. Family Practice. 2010; 27:263-70.


A. Katsarou, S. Tyrovolas, T. Psaltopoulou, A. Zeimbekis, N. Tsakountakis, V. Bountziouka, E. Gotsis, G. Metallinos, E. Polychronopoulos, C. Lionis, D. Panagiotakos. Socio-economic status, place of residence and dietary habits among the elderly: the Mediterranean islands study. Public Health Nutrition 2010; 13:1614-21.


N. Daniilidou, S. Gregory, D. Zavras, E. Pavi, K. Athanasakis, C. Lionis, J. Kyriopoulos. Comparison between two different measures of self-rated health: a single-question measure and a visual analogue scale. Folia Medica 2010; 52:63-9.


S. Tyrovolas, G. Pounis,  A. Zeimbekis, M. Antonopoulou, V. Bountziouka, E. Gotsis, G. Metallinos, A. Polystipioti, E. Polychronopoulos, C. Lionis, D. B. Panagiotakos. Associations of energy intake and type 2 diabetes with hypertryglyceridemia in older adults living in the Mediterranean islands: the MEDIS study. Journal of Nutrition for the Elderly 2010; 29:72-86.


T. Abu-Mourad, A. Koutis, A. Alegakis, A. Markaki, C. Jildeh, C. Lionis, A. Philalithis. Self-reported health complaints in a primary care population living under stressful conditions in Gaza Strip, Palestine. Medicine, Conflict and Survival Journal 2010; 26:68-79.


L. Bjerrum, A. Munck, B. Gahrn-Hansen, M. P. Hansen, D. Jarboel, C. Llor, J. M. Cots, S. Hernαndez, B. G. Lσpez-Valcαrcel, A. Pιrez, L. Caballero, W. von der Heyde, R. Radzeviviene, A. Jurgutis, A. Reutskiy, E. Egorova, E. L. Strandberg, I. Ovhed, S. Molstad, R. vander Stichele, R. Benko, V. Vlahovic-Palcevski, C. Lionis, M. Rønning. Health Alliance for Prudent Prescribing, Yield and Use of Antimicrobial Drugs in the Treatment of Respiratory Tract Infections (HAPPY AUDIT). BioMed Central Family Practice 2010; 11:29.


C. Kruschinski, M. Lange, C. Lionis, C. van Weel, E. Hummers-Pradier; EGPRN. Themes and methods of research presented at European General Practice Research Network conferences. Family Practice 2010; 27:459-67.


P. Van Royen, M. Beyer, P. Chevallier, S. Eilat-Tsanani, C. Lionis, L. Peremans, D. Petek, I. Rurik, J. K. Soler, H. E. Stoffers, P. Topsever, M. Ungan, E. Hummers-Pradier. The research agenda for general practice/family medicine and primary health care in Europe. Part 3. Results: person centred care, comprehensive and holistic approach. European Journal of General Practice 2010; 16:113-9.


P. Van Royen, H. Sandoholzer, F. Griffiths, C. Lionis, J. J. Rethans, F. Gali, S. Eilat, P. van Royen. Are abstracts presented at EGPRN meetings followed by publication? European Journal of General Practice 2010; 16:100-5.


H. Pinnock, M. Thomas, I. Tsiligianni, K. Lisspers, A. Østrem, B. Ställberg, O. Yusuf, D. Ryan, J. Buffels, JW. Cals, NH. Chavannes, SH. Henrichsen, A. Langhammer, E. Latysheva, C. Lionis, J. Litt, T. van der Molen, N. Zwar, S. Williams. The International Primary Care Respiratory Group (IPCRG) Research Needs Statement 2010. Primary Care Respiratory Journal 2010; 1:S1-20. 


C. I. Vardavas, C. Lionis, E. Polychronopoulos, A. Zeibekis, V. Bountziouka, P. Stavopodis, G. Metallinos, D. P. Panagiotakos. The role of second hand smoking on the prevalence of type II diabetes mellitus among elderly men and women living in Mediterranean islands: the MEDIS study. Diabetic Medicine 2010; 27:242-8.


P. Msaouel, N. C.  Keramaris, A. Tasoulis, D. Kolokythas, N. Syrmos, N. Pararas,  E. Thireos, C. Lionis. Burnout and training satisfaction of medical residents in Greece: will the European Work Time Directive make a difference? Human Resources for Health 2010; 8:16.


E. Mamplekou, V. Bountziouka, T. Psaltopoulou, A. Zeimbekis, N. Tsakoundakis, N. Papairakleous, E. Gotsis, G. Metallinos, G. Pounis, E. Polychronopoulos, C. Lionis, D. B. Panagiotakos. Urban environment, physical inactivity and unhealty dietary habits correlate to depression among elderly living in eastern Mediterranean islands; the MEDIS (MEDiterranean ISlands Elderly) Study. Journal of Nutrition Health Aging 2010; 14:449-55.


I. G. Tsiligiani, T. Van der Molen, N. E. Tzanakis, N. M. Siafakas, E. Van Heijst, C. Lionis. A telehealth integrated asthma-COPD service for primary care: a proposal for a pilot feasibility study in Crete, Greece. BMC Research Notes. 2010; 3:198.


E. Germeni, C. Lionis, V. Kalampoki, B. Davou, M, Belechri, E. Petridou. Evaluating the impact of a school-based helmet promotion program on eligible adolescent drivers: different audiences, different needs? Health Education Research 2010; 25:865-76.


M. Yannakoulia, S. Tyrovolas, V. Bountziouka, N. Papaerakleous, A. Zeimbekis, M. Antonopoulou, E. Gotsis, G. Metallinos, E. Polychronopoulos, C. Lionis, D. B. Panagiotakos. The mediating effect of physical activity and smoking on the relationship between coffee drinking and body weight in elderly individuals; the Mediterranean Islands study. Journal of the American Geriatrics Society 2010; 58:1208-10.


H. Baumgartner, P. Bonhoeffer, N. M. De Groot, F. de Haan, J. E. Deanfield, N. Galie, M. A. Gatzoulis, C. Gohlke-Baerwolf, H. Kaemmerer, P. Kilner, F. Meijboom, B. J. Mulder, E. Oechslin, J. M. Oliver, A. Serraf, A. Szatmari, E. Thaulow, P. R. Vouhe, E. Walma, A. Vahanian, A. Auricchio, J. Bax, C. Ceconi, V. Dean, G. Filippatos, C.  Funck-Brentan, R. Hobbs, P. Kearney, T. McDonagh, B. A. Popescu, Z. Reiner, U. Sechtem, P. A. Sirnes, M. Tendera, P. Vardas, P. Widimsky, T. McDonagh, L. Swan, F. Andreotti, M. Beghetti, M. Borggrefe, A. Bozio, S. Brecker, W. Budts, J. Hess, R. Hirsch, G. Jondeau, J. Kokkonen, M. Kozelj, S. Kucukoglu, M. Laan, C. Lionis, I. Metreveli, P. Moons, P. G. Pieper, V. Pilossof, J. Popelova, S. Price, J. Roos-Hesselink, M. S. Uva, P. Tornos, P. T. Trindade, H. Ukkonen, H. Walker, G. D. Webb, J. Westly; Task Force on the Management of Grown-up Congenital Heart Disease of the European Society of Cardiology (ESC). Esc guidelines for the management of grown-up congenital heart disease (new version 2010). European Heart Journal 2010; 31:2915-57.


E. Hummers-Pradier, M. Beyer, P. Chevallier, S. Eilat-Tsanani, C. Lionis, L. Peremans, D. Petek, I. Rurik, J. K. Soler, H. E. Stoffers, P.  Topsever, M. Ungan, P. van Royen. The research agenda for general practice/family medicine and primary health care in Europe. Part 4. Results: specific problem solving skills. European Journal of General Practice 2010; 16:174-81.


G. D. Pounis, S. Tyrovolas, M. Antonopoulou, A. Zeimbekis, F. Anastasiou, V. Bountziouka, G. Metallinos, E. Gotsis, E. Lioliou, E. Polychroniou, C. Lionis, D. B. Panagiotakos. Long-term animal protein consumption is associated with an increased prevalence of diabetes among the elderly: the Mediterranean Islands (MEDIS) study. Diabetes and Metabolism 2010; 36:484-90.


C. Lionis, D. Anyfantakis, E. K. Symvoulakis, S. Shea, D. B. Panagiotakos, E. Castanas. Bio-psychosocial determinants of cardiovascular disease in a rural population on Crete, Greece: formulating a hypothesis and designing the SPILI-III study. BioMed Central Research Notes 2010; 3:258.


E. Symvoulakis, D. Anyfantakis, C. Lionis. Restless legs syndrome: literature review. Sao Paulo Medical Journal 2010; 128:167-70.


E. K. Symvoulakis, D. I. Anyfantakis, C. Lionis. Primary lower limb lymphedema: a focus on its functional, social and emotional impact. International Journal of Medical Sciences 2010; 7:353-7.


E. Polychronopoulos, V. Bountziouka, A. Zeimbekis, I. Tsiligiani, G.  Pounis, E. Gotsis, G. Metallinos, C. Lionis, D. B. Panagiotakos. Dietary fats in relation to depressive symptoms by cardiovascular disease risk factors status of elderly people living in Mediterranean islands. International Journal of Food Sciences and Nutrition 2010. [Epub ahead of print].


P. Van Royen, M. Beyer, P. Chevallier, S. Eilat-Tsanani, C. Lionis, L. Peremans, D. Petek, I. Rurik, J. K.  Soler, H. E. Stoffers, P. Topsever, M. Ungan, E. Hummers-Pradier. The research agenda for general practice/family medicine and primary health care in Europe. Part 5: Needs and implications for future research and policy. European Journal of General Practice 2010; 16:244-48.


S. Shea and C. Lionis. Restoring humanity in health care through the art of compassion: an issue for the teaching and research agenda in rural health care. Rural Remote Health. 2010; 10:1679.






S. Tyrovolas, T. Psaltopoulou, G. Pounis, N. Papairakleous, V. Bountziouka, A. Zeimbekis, E. Gotsis, M. Antonopoulou, G. Metallinos, E. Polychronopoulos, C. Lionis, D. B. Panagiotakos. Nutrient intake in relation to central and overall obesity status among elderly people living in the Mediterranean islands: the MEDIS study. Nutrition, metabolism, and cardiovascular diseases 2011; 21:438-45.


 S. Tyrovolas, C. Chalkias, M. Morena, I. Tsiligianni, A. Zembekis, E. Gotsis, G. Metallinos, V. Bountziouka, E. Polychronopoulos, C. Lionis, D. Panagiotakos. Health care access and prevalence of the metabolic syndrome among elders living in high-atitude areas of Mediterannean islands: the MEDIS study. The Review of Diabetic Studies 2011; 8:468-76.


M. Trigoni, M. C.  Mahoney, J.  Moschandreas, D. Tsiftsis, E.  Koumantakis, C. Lionis. Approaches to Breast Cancer Screening Among Primary Care Physicians in Rural Areas of Crete, Greece. Journal of Cancer Education 2011; 26:490-6.


 P. Van Royen, M. Beyer, P. Chevallier, S. Eilat-Tsanani, C. Lionis, L.  Peremans, D. Petek, I. Rurik, J. K. Soler, H. E. Stoffers, P.  Topsever, M. Ungan, E. Hummers-Pradier. The research agenda for general practise/family medicine and primary health care in Europe. Part 6: reaction on commentaries-how to continue with the Research Agenda? European Journal of General Practice 2011; 17:58-61.


E. Oikonomidou, F.  Anastasiou, I.  Pipilidis, E.  Kouroumalis, C. Lionis; Greek General Practise Dyspepsia Group. Upper gastrointestinal endoscopy for dyspepsia: Exploration study of factors influencing patient compliance in Greece. BioMed Central Gastroenterology 2011; 11:11.


 M. Yannakoulia, S. Tyrovolas, G. Pounis, A. Zeimbekis, F. Anastasiou, V. Bountziouka, K. Voutsa, E. Gotsis, G. Metallinos, C. Lionis, E.  Polychronopoulos, D. Pnagiotakos. Correlates of low dietary energy reporting in free-living elderly: the MEDIS study. Maturitas 2011; 69:63-8.


E. Kuhlmann, V. Burau, C. Larsen, R.  Lewandowski, C. Lionis, J. Repullo. Medicine and management in European healthcare systems: how do they matter in the control of clinical practise? International Journal of Clinical Practice 2011; 65:722-4.


 L. Bjerrum, B. Gahrm-Hansen, M. P. Hansen, D. E. Jarbol, G. Cordoba, C. Llor, J. M. Cots, S. HernandezB. G. Lopez-ValcarcelA. Perez, L. Caballero, W. vonderHeyde, R. Radzeviciene, A. Jurguitis, A. Reutskiy, E. EgorovaE. L. Strandberg, I. Ovhed, S. Molstad, R. V. Stichele, R. Benko, V. Vlahovic-Palcevski, C. Lionis, M. Ronning. Health Alliance for prudent antibiotic prescribing in patients with respiratory tract infections (HAPPY AUDIT)-impact of a non randomised multifaceted intervention programme. BioMed Central Family Practice 2011; 12:52.


E. Andreou, E. C. Alexopoulos, C. Lionis, C. Gnardelis, G. P. Chrousos, C. Darviri. Perceived Stress Scale: Reliability and Validity Study. International Journal of Environmental Research and Public Health 2011; 8:3287-98.


 C. Lionis and E. Petelos. Early detection of colorectal cancer: barriers to screening in the primary care setting. Family Practice 2011; 28:589–91.


M. Ollandezos, T. Constantinidis, K. Athanasakis, C. Lionis, J. Kyriopoulos. Trends of mortality in Greece 1980-2007: a focus on avoidable mortality. Hippokratia 2011; 15:330-4.


 W. Qidwai, T. Ashfag, T. A. M. Khoja, K. Merchant, A. Seneviratne, A. E. Fahim, A. Al-Arafah, A. Hussain,  B. L. Lovell, B. Cayley, C. Lionis, F. A. Alnasir, H. Yaman, J. Kenkre, L. Pocock, L. Becker, M. Jamoulle, M. S. Hussein, N. Qureshi, O. Ayankogbe, S. Sunwoo.Εquity in Health Care: Status, Barriers, and Challenges. Middle East Journal of Family Medicine 2011; 9:36-41.


C. D. Lionis, C. I. Vardavas, E. K. Symvoulakis, M. G Papadakaki, F. S. Anastasiou, M. D. Antonopoulou, C. M. Apostolakis, S. A. Dimitrakopoulos, G. I. Fountakis, I. A. Grammatikopoulos, J. D. Komninos, D. K. Kounalakis, E. S. Ladoukaki, K. V. Makri, C. S. Petraki, N. G. Ploumis, D. P. Prokopiadou, I. N. Stefanaki, N. A. Tsakountakis, I. G. Tsiligianni, E. N. Tzortzis, A. A. Vasilaki, T. K. Vasilopoulos, G. E. Vrentzos. Measuring the burden of herpes zoster and post herpetic neuralgia within primary care in rural Crete, Greece. BioMed Central Family Practice 2011; 12:136.


 C. Lionis, S. Shea, A. Markaki. Introducing and implementing a compassionate care elective for medical students in Crete. Journal of Holistic Healthcare 2011; 8:38-41.


S. Shea, R. Wynyard, E. West, C. Lionis. Reaching a consensus in defining and moving forward with the science and art of compassion in healthcare. Journal of Holistic Healthcare 2011; 8:58-60.






I. G. Tsiligianni, C. Delgatty, A. Alegakis, C. Lionis. A household survey on the extent of home medication storage. A cross-sectional study from rural Crete, Greece. European Journal of General Practice 2012; 18:3-8.


E. A. Smpokos, M. Linardakis, A. Papadaki, C. Lionis, A. Kafatos. Secular trends in fitness, moderate-to-vigorous physical activity, and TV-viewing among first grade children of Crete, Greece between 1992/93 and 2006/07. Journal of Science and Medicine in Sport 2012; 15:129-35.


G. Moschonis, G. P. Chrousos, C. Lionis, V. Mougios, Y. Manios. Association of total body and visceral fat mass with iron deficiency in preadolescents: the Health Growth Study. British Journal of Nutrition 2012; 108:710-9.


M. Papadakaki, D. Prokopiadou, E. Petridou, M. Kogevinas, C. Lionis. Defining Physicians’ Readiness to Screen and Manage Intimate Partner Violence in Greek Primary Care Settings. Evaluation & the Health Professions 2012; 35:199-220.


A. Papathanasiou, A. Koutsovasilis, S. Shea, A. Philalithis, Spapavasiliou, A. Melodonis, C. Lionis. The Problem Areas In Diabetes (PAID) scale: psychometric evaluation survey in a Greek sample with Type 2 diabetes. Journal of Psychiatric and Mental Health Nursing 2012; doi:10.1111/j.1365-2850.2012.01875.x.


C. I. Vardavas, N. Anagnostopoulos, M. Minas, C. Nakou, V. Dramba, E. Patelarou, G. Giourgouli, E. Bagkeris, K. Gourgoulianis, P. Pattaka, A. Antoniadis, C. Lionis, M. Bertic, D. Dockery, G. N. Connolly, P. Behrakis. Five year trends of second-hand smoke exposure in Greece: A comparison between complete, partial and pre legislation levels. Journal of Aerosol Medicine and Pulmonary Drug Delivery 2012; 25:349-54.


C. Lionis, E. K. Symvoulakis, G. Duijker, F. Anastasiou, S. Dimitrakopoulos, C. Kladou, E.  Ladoukaki, K. Makri, C. Petraki, N. Sivaropoulos, S. Sasarolis, A. Stefanaki, A. Vasilaki, T. Vasilopoulos. Reporting new cases of anaemia in primary care settings in Crete, Greece: a rural practice study. Asia Pacific Family Medicine 2012; 11:4.


L. Chatzi, K. Koutra, M. Vassilaki, V. Georgiou, A. Koutis, C. Lionis, P. Bitsios, M. Kogevinas. Maternal personality traits and risk of preterm birth and fetal growth restriction. European Psychiatry 2012; doi:10.1016/j.eurpsy.2011.11.006.


V. Vivilaki, V. Dafermos, L. Gevorgian, E. Patelarou, D. Bick, N. Chopelas, C. Lionis. Validation of the Greek maternal adjustment and maternal attitudes scale for assessing early postpartum adjustment. Women & Health 2012; 52:369–90.


N. Kakoliris, E. Symvoulakis, K. Antoniou, I. Grammatikopoulos, N. Tzanakis, N. Siafakas, C. Lionis. A snapshot of primary care physicians educational needs regarding COPD in Crete, Greece: an exploratory case study. HealthMED 2012; 6:781-6.


E. Oikonomidou, C. Mihas, F. Anastasiou, C. Lionis. Validation of the reflux disease questionnaire into Greek. Gastroenterology Insights 2012; 4:e20.


C. Lionis and S. Shea. Enhancing compassionate care as an integral part of primary care and general practice. Global Journal of Medicine and Public Health 2012; 1:5.


K. Koutra, S. Triliva, C. Roumeliotaki, C. Lionis, A. Vbontzas. Cross-cultural adaptation and validation of the Greek version of the Family Adaptability and Cohesion Evaluation Scale IV Package (FACES IV). Journal of Family Issues 2012; doi:10.1177/0192513X12462818. [Epub ahead of print].


V. Sbarouni, Z. Tsimtsiou, E. Symvoulakis, A. Kamekis, E. Petelos, A. Saridaki, N. Papadakis, C. Lionis. Perceptions of primary care professionals on quality of services in rural Crete: a qualitative study. Rural and Remote Health Journal 2012; 12:2156.


C. I. Vardavas, C. Girvalaki, L. Lazuras, D. Triantafylli, C. Lionis, G. N. Connolly, P. Behrakis. Changes in tobacco industry advertising around high schools in Greece following an outdoor advertising ban: a follow-up study. Tobacco Control 2012; [Epub ahead of print].


A. MacFarlane, C. O'Donnell, F. Mair, M. O'Reilly-de Brún, T. de Brún, W. Spiegel, M. van den Muijsenbergh, E. van Baumgarten, C. Lionis, N. Burns, K. Gravenhorst, C. Princz, E. Teunissen, F. van den Driessen Mareeuw, A. Saridaki, M. Papadakaki, M. Vlahadi, C. Dowrick. REsearch into implementation STrategies to support patients of different ORigins and language background in a variety of European primary care settings (RESTORE): study protocol. Implementation Science 2012; 7:111.


C. Lionis and A. Tatsioni. Conducting research in rural primary care medicine: do we need more experimental research or guidance? Rural Remote Health 2012; 12:2267.


A. Kousoulis, E. Symvoulakis, C. Lionis. What Greece can learn from UK primary care experience and empirical research? British Journal of General Practice 2012; 62:543.


Y. Manios, G. Moschonis, G. P. Chrousos, C. Lionis, V. Mougios, M. Kantilafti, V. Tzotzola, K. P. Skenderi, A. Petridou, G. Tsalis, A. Sakellaropoulou, G. Skouli, C. Katsarou. The double burden of obesity and iron deficiency on children and adolescents in Greece: the Healthy Growth Study. Journal of Human Nutrition and Dietetics 2012; doi:10.1111/jhn.12025. [Epub ahead of print].


C. Lionis and F. Anastasiou. Gastroenterology in Primary Care in Greece: a short report. Journal of Primary Care Society Gastroenterology 2012; 4:13-6.






C. Athanasopoulos, P. M. Pitychoutis, I. Messari, C.  Lionis, Z. Papadopoulou-Daifoti. Is Drug Utilization in Greece Sex dependent? A Population-based Study. Basic and Clinical Pharmacology and Toxicology 2012; 112:55-62.


V. Dimitriadis, A. A. Kousoulis, A. Markaki, M. N. Sgantzos, A. Hadjipavlou, C. Lionis. Quality assessment in rehabilitation services for the disabled in Greece: A critical review. Disability and Health Journal 2013; doi:10.1016/j.dhjo.2013.01.005. [Epub ahead of print].


G. Moschonis, C. Mavrogianni, K. Karatzi, V. Iatridi, G. P. Chrousos, C. Lionis, Y. Manios. Increased physical activity combined with more eating occasions is beneficial against dyslipidaemias in children. The Healthy Growth study. European Journal of Nutrition 2012; doi:10.1007/s00394-012-0424-3.


Y. Manios, M. Birbilis, G. Moschonis, G. Birbilis, V. Mougios, C. Lionis, G. P. Chrousos; on behalf of the “Healthy Growth Study” group. Childhood Obesity Risk Evaluation based on perinatal factors and family sociodemographic characteristics: CORE Index. European Journal of Pediatrics. 2013; doi:10.1007/s00431-012-1918-y. [Epub ahead of print].


V. Tsiantou, S. Shea, L. Martinez, D. Agius, O. Basak, T. Faresjö, J. Moschandreas, G. Samoutis, E. K. Symvoulakis, C. Lionis. Eliciting general practitioners' salient beliefs towards prescribing: A qualitative study based on the Theory of Planned Behaviour in Greece. Journal of Clinical Pharmacy and Therapeutics 2013; doi:10.1111/jcpt.12037. [Epub ahead of print].


D. Prokopiadou, M. Papadakaki, T. Roumeliotaki, I. D. Komninos, C. Bastas, E. Iatraki, A. Saridaki, A. Tatsioni, A. Manyon, C. Lionis. Translation and Validation of a Questionnaire to Assess the Diagnosis and Management of Dementia in Greek General Practice. Evaluation and the Health Professions 2013; doi:10.1177/0163278712474988. [Epub ahead of print].


V. Sapouna, V. Dafermos, M. Chatziarsenis, V. Vivilaki, P. Bitsios, A. H. Schene, C. Lionis. Assessing the burden of caregivers of patients with mental disorders: translating and validating the Involvement Evaluation Questionnaire into Greek. Annals of General Psychiatry 2013; 12:3.


C. I. Vardavas, E. K. Symvoulakis, C. Lionis. Dealing with tobacco use and dependence within primary health care: time for action. Tobacco Induced Diseases 2013; 11:6.


I. Tsiligianni, F. Athanasiou, M. Antonopoulou, K. Chliveros, S. Dimitrakopoulos, G. Duijker, D. Kounoulakis, K. Makri, C. Petraki, D. Prokopiadou, I. Stefanaki, E. Symvoulakis, N. Tsakountakis, T. Vasilopoulos, C. Vittorakis, C. Lionis. Greek rural GPs’ opinions on how financial crisis influence health, quality of care and health equity. Rural and Remote Health; 13:2528.


G. Moschonis, A. C. Kalliora, V. Costarelli, C. Papandreou, D. Koutoukidis, C. Lionis, G. P Chrousos, Y. Manios. Identification of lifestyle patterns associated with obesity and fat mass in children: the Healthy Growth Study.  Public Health Nutrition 2013; 26:1-11. doi:10.1017/S1368980013000323. [Epub ahead of print].


M. Papadakaki, E. Petridou, M. Kogevinas, C. Lionis. Measuring the effectiveness of an intensive IPV training program offered to Greek general practitioners and residents of general practice. BioMed Central medical education 2013; 13:46. [Epub ahead of print].


A. A. Kousoulis, K. E. Angelopoulou, C. Lionis. Exploring health care reform in a changing Europe: Lessons from Greece. European Journal of General Practice 2013; 1-6. [Epub ahead of print].


P. Mallaina, C. Lionis, H. Rol, R. Imperiali, A. Burgess, M. Nixon F. Mondello-Malvestiti. Smoking Cessation and the Risk of Cardiovascular Disease Outcomes Predicted from Established Risk Scores:  Results of the Cardiovascular Risk Assessment among Smokers in Primary Care in Europe: (CV-ASPIRE) Study. BioMed Cetral Public Health 2013; 13:362.  [Epub ahead of print].


M. van den Muijsenbergh, E. van Weel-Baumgarten, N. Burns, C. O'Donnell, F. Mair, W. Spiegel, C. Lionis, C. Dowrick, M. O'Reilly-de Brún, T. de Brun, A. Macfarlane. Communication in cross-cultural consultations in primary care in Europe: the case for improvement. The rationale for the RESTORE FP 7 project. Primary Health Care Research & Development 2013; 22:1-12. [Epub ahead of print].


G. Moschonis, V. Mougios, C. Papandreou, C. Lionis, G. P. Chrousos, E. Malandraki, Y. Manios. "Leaner and less fit" children have a better cardiometabolic profile than their "heavier and more fit" peers: The Healthy Growth Study. Nutrition, Metabolism and Cardiovascular Diseases 2013; 1-8. [Epub ahead of print].


V. Dimitriadis, A. A. Kousoulis, A. Markaki, M. N. Sgantzos, A. Hadjipavlou, C. Lionis. Quality assessment systems in rehabilitation services for people with a disability in Greece: A critical review. Disability and health journal 2013; 6:157-64.


E. Kuhlmann, V. Burau, T. Correia, R. Lewandowski, C. Lionis, M. Noordegraaf, J. Repullo. A manager in doctors' mind: A comparison of new modes of control in European hospitals
Journal. BioMed Central Health Services Research 2013; 13:246.


Y. Manios, G. Moschonis, C. Papandreou, P. E. Siatitsa, V. Iatridi, I. Lidoriki, C. Lionis, Chrousos On Behalf Of The Healthy Growth Study Group GP. Female sex, small size at birth and low family income increase the likelihood of insulin resistance in late childhood: the Healthy Growth Study. Pediatric Diabetes 2013; [Epub ahead of print].


K. Merakou, A. Koutsouri, E. Antoniadou, A. Barbouni, A. Bertsias, G. Karageorgos, C. Lionis. Sense of coherence in people with and without type 2 diabetes mellitus: an observational study from Greece. Mental Health in Family Medicine 2013; 10:3–13.


D. Anyfantakis, E. K. Symvoulakis, D. B. Panagiotakos, D. Tsetis, E. Castanas, S. Shea, M. Venihaki, C. Lionis. Impact of religiosity/spirituality on biological and preclinical markers related to cardiovascular disease. Results from the SPILI III study. Hormones (Athens) 2013; 12:386-96.


C. O’Donnell, N. Burns, C. Dowrick, C. Lionis, A. MacFarlane, on behalf of the RESTORE team. Health-care access for migrants in Europe. The Lancet 2013; 393.


E. Tourlouki, A. L. Matalas, V. Bountziouka, S. Tyrovolas, A. Zeimbekis, E. Gotsis, I. Tsiligianni, I. Protopapa, C. Protopapas, G. Metallinos, C. Lionis, S. Piscopo, E. Polychronopoulos, D. B. Panagiotakos. Are Current Dietary Habits in Mediterranean Islands a Reflection of the Past? Results from the MEDIS Study. Ecology of Food and Nutrition 2013; 52:371-86.


A. P. Hungin, C. Mulligan, B. Pot, P. Whorwell, L. Agréus, P. Fracasso, C. Lionis, J. Mendive, J. M. Philippart de Foy, G. Rubin, C. Winchester, N. de Wit; European Society for Primary Care Gastroenterology. Systematic review: probiotics in the management of lower gastrointestinal symptoms in clinical practice - an evidence-based international guide. Alimentary pharmacology & therapeutics 2013; doi: 10.1111/apt.12460. [Epub ahead of print].


I. Drositis, A. Bertsias, C. Lionis, E. Kouroumalis. Epidemiology and molecular analysis of hepatitis A, B and C in a semi-urban and rural area of Crete. European Journal of Internal Medicine 2013; [Epub ahead of print].


C. Athanasopoulou, H. Hätönen, S. Suni, C. Lionis, K. M. Griffiths, M. Välimäki. An analysis of online health information on schizophrenia or related conditions: a cross-sectional survey. BioMed Central medical informatics and decision making 2013; 13(1):98.


C. I. Vardavas, I. Agaku, E. Patelarou, N. Anagnostopoulos, C. Nakou, V. Dramba, G. Giourgouli, P. Argyropoulou, A. Antoniadis, K. Gourgoulianis, D. Ourda, L. Lazuras, M. Bertic, C. Lionis, G. Connolly, P. Behrakis; Hellenic Air Monitoring Study Investigators. Ashtrays and Signage as Determinants of a Smoke-Free Legislation's Success. PLoS One 2013; 8:e72945.


Lopez-Abuin and C. Lionis. EURIPA: EUROPEAN RURAL AND ISOLATED PRACTITIONERS ASSOCIATION 4th EURIPA Rural Health Invitational Forum/77th EGPRN Workshop: EURIPA-EGPRN joint meeting. The European journal of general practice 2013; 19(3):205-6.


C. Lionis and E. Petelos. The impact of the financial crisis on the quality of care in primary care: an issue that requires prompt attention. Quality in Primary Care 2013; 21:269-273.


 C. Lionis. Common Pitfalls When Reporting General Practice/Family Medicine Research: Simple Recommendations to Prevent Them. Journal of General Practice 2013; 1:3.


S. Bellos, P. Skapinakis, D. Rai, P. Zitko, R. Araya, G. Lewis, C. Lionis, V. Mavreas. Cross-cultural patterns of the association between varying levels of alcohol consumption and the common mental disorders of depression and anxiety: Secondary analysis of the WHO Collaborative Study on Psychological Problems in General Health Care. Drug and alcohol dependence 2013; [Epub ahead of print].


E. Iatraki, P. G. Simos, C. Lionis, I. Zaganas, E. K. Symvoulakis, E. Papastefanakis, S. Panagiotakis, H. Pantelidakis, K. Papadopoulos, C. Tziraki. Cultural Adaptation, Standardization and Clinical Validity of the Test Your Memory Dementia Screening Instrument in Greek. Dementia and geriatric cognitive disorders 2013; 37:163-180. [Epub ahead of print].


Y. Manios, G. Moschonis, C. Papandreou, E. Politidou, A. Naoumi, D. Peppas, C. Mavrogianni, C. Lionis, G. P. Chrousos; on behalf of the ‘Healthy Growth Study’ group. Revised Healthy Lifestyle-Diet Index and associations with obesity and iron deficiency in schoolchildren: The Healthy Growth Study. Journal of human nutrition and dietetics 2013; [Epub ahead of print].


G. Moschonis, V. Mougios, C. Lionis, G. P. Chrousos, Y. Manios. Response to the Letter to the Editor: We're not ready to encourage children to be "Lean" rather than "Fit". Nutrition, metabolism, and cardiovascular diseases 2013; [Epub ahead of print].


K. M. Antoniou, E. K. Symvoulakis, G. A. Margaritopoulos, C. Lionis, A. U. Wells. Early diagnosis of IPF: time for a primary-care case-finding initiative? The Lancet Respiratory Medicine 2014; 2:e1.


S. Tyrovolas, C. Chalkias, K. Kalogeropoulos, M. Morena, N. Tsakountakis, A. Zeimbekis, E. Gotsis, G. Metallinos, V. Bountziouka, C. Lionis, E. Polychronopoulos, D. Panagiotakos. High relative environmental humidity is associated with diabetes prevalence among elders: the MEDIS study. Journal of Diabetes & Metabolic Disorders 2014; (in press).


K. Koutra, A. N. Vgontzas, C. Lionis, S. Triliva. Family functioning in first-episode psychosis: a systematic review of the literature. Social psychiatry and psychiatric epidemiology 2014; [Epub ahead of print].

261 G. Moschonis, D. Papandreou, C. Mavrogianni, A. Giannopoulou, L. Damianidi, P. Malindretos, C. Lionis, G. P. Chrousos, Y. Manios. Association of iron depletion with menstruation and dietary intake indices in pubertal girls: the healthy growth study. BioMed research international 2013; 2013:423263.
262 A. Macfarlane, M. O'Reilly-de Brún, C. de Brún T, Dowrick, C. O'Donnell, F. Mair, W. Spiegel, M. van den Muijsenbergh, E. van Weel Baumgarten, C. Lionis, C. Clissmann; on behalf of the RESTORE consortium. Healthcare for migrants, participatory health research and implementation science-better health policy and practice through inclusion. The RESTORE project. The European journal of general practice 2014; [Epub ahead of print].

K. Karatzi, G. Moschonis, A. A. Barouti, C. Lionis , G. P. Chrousos, Y. Manios. Dietary patterns and breakfast consumption in relation to insulin resistance in children. The Healthy Growth Study. Public Health Nutrition 2014; 15:1-8.


C. Lionis, E. Petelos, S. Shea, G. Bagiartaki, I. G. Tsiligianni, A. Kamekis, V. Tsiantou, M. Papadakaki, A. Tatsioni, J. Moschandreas, A. Saridaki, A. Bertsias, T. Faresjö, A. Faresjö, L. Martinez, D. Agius, Y. Uncu, G. Samoutis, J. Vlcek, A. Abasaeed, B. Merkouris. Irrational prescribing of over-the-counter (OTC) medicines in general practice: testing the feasibility of an educational intervention among physicians in five European countries. BioMed Central family practice 2014; 15:34. [Epub ahead of print].


J. Koetsenruijter, J. van Lieshout, I. Vassilev, M. C. Portillo, M. Serrano, I. Knutsen, P. Roukova, C. Lionis, E. Todorova, C. Foss, A. Rogers, M. Wensing. Social support systems as determinants of self-management and quality of life of people with diabetes across Europe: study protocol for an observational study. Health and Quality of Life Outcomes 2014; 12:29.


K. Koutra, M. Economou, S. Triliva, T. Roumeliotaki, C. Lionis, A. N. Vgontzas. Cross-cultural adaptation and validation of the Greek version of the Family Questionnaire for assessing expressed emotion. Comprehensive psychiatry 2014; [Epub ahead of print].


I. G. Tsiligianni, S. Tyrovolas, V. Bountziouka, A. Zeimbekis, E. Gotsis, G. Metallinos, D. Tyrovola, E. Polychronopoulos, C. Lionis, D. Panagiotakos. Depressive symptoms in postmenopausal women: Results from the MEDIS Study. Women Health 2014; [Epub ahead of print].


I. N. Stefanaki, S. Shea, M. Linardakis, E. K. Symvoulakis, R. Wynyard, C. Lionis. Exploring the association of Sense of Coherence, and Spiritual and Religious Beliefs in a rural population group on the island of Crete,Greece. International Journal of Psychiatry in Medicine; 47:207-30.


A. A. Reutskiy, L. Bierrum, A. Munck, B. Gahrn-Hansen, M. P. Hansen, B. G. Lopez-Valkarsel, L. Caballero, R. Radzeviciene, C. Llor, E. L. Strandberg, I. Ovhead, C. Lionis. Indicators of the antibiotics prescription to treat of respiratory tract infection (RTI) in general practice. General Practitioner Handbook 2014; 6


S. Tyrovolas, J. M. Haro, E. Polychronopoulos, A. Mariolis, S. Piscopo, G. Valacchi, K. Makri, A. Zeimbekis, D. Tyrovola, V. Bountziouka, E. Gotsis, G. Metallinos, Y. Katsoulis, J. A. Tur, A. Matalas, C. Lionis, D. Panagiotakos. Factors associated with components of arterial pressure among older individuals (the multinational medis study): the role of the mediterranean diet and alcohol consumption. J Clin Hypertension 2014; [Epub ahead of print].


A. Bertsias, I. G. Tsiligianni, G. Duijker, N. Siafakas, C. Lionis; on behalf of the Cretan CAP Research Group. Studying the burden of community-acquired pneumonia in adults aged ≥ 50 years in primary health care: an observational study in rural Crete, Greece. NPJ Primary Care Respiratory Medicine 2014; [Epub ahead of print].


K. Koutra, S. Triliva, T. Roumeliotaki, C. Lionis, A. N. Vgontzas. Identifying the socio-demographic and clinical determinants of family functioning in Greek patients with psychosis. The International journal of social psychiatry 2014; [Epub ahead of print].


K. Koutra, S. Triliva, T. Roumeliotaki, Z. Stefanakis, M. Basta, C. Lionis, A. N. Vgontzas. Family functioning in families of first-episode psychosis patients as compared to chronic mentally ill patients and healthy controls. Psychiatry research 2014; [Epub ahead of print].


P. M. Elliott, A. Anastasakis, M. A. Borger, M. Borggrefe, F. Cecchi, P Charron, A. A. Hagege, A. Lafont, G. Limongelli, H. Mahrholdt, W. J. McKenna, J. Mogensen, P. Nihoyannopoulos, S. Nistri, P. G. Pieper, B. Pieske, C. Rapezzi, F. H. Rutten, C. Tillmanns, H. Watkins; Authors/Task Force members. 2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy: The Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC). European heart journal 2014; [Epub ahead of print].


275. A. Kennedy, A. Rogers, I. Vassilev, E. Todorova, P. Roukova, C. Foss, I. Knutsen, M.C. Portillo, A. Mujika, M.Serrano-Gil, C. Lionis, A. Agelaki, N. Ratsika, J. Koetsenruijter, M. Wensing. Dynamics and nature of support in the personal networks of people with type 2 diabetes living in Europe: qualitative analysis of network properties. Health Expectations 2014.


C. Lionis. Ethnic and social disparities in medical education. Medical Education 2014; 49: 7-20.


A. Kousoulis, E. Patelarou, S. Shea, C. Foss, I.A. Ruud Knutsen, E. Todorova, P. Roukova, M.C. Portillo, M.J. Pumar-Mendez, A. Mujika, A. Rogers, I. Vassilav, M. Serrano-Gil, C. Lionis. Diabetes self-management arrangements in Europe: a realist review to facilitate a project implemented in six countries. BMC Health Serv Res. 2014; 14:453.


S. Tyrovolas, J.M, Haro, A. Mariolis, S. Piscopo, G. Valacchi, N. Tsakountakis, A. Zeimbekis, D. Tyrovola, V. Bountziouka, E. Gotsis, G. Metallinos, J.A. Tur, A.L Matalas, C. Lionis, E. Polychronopoulos, D. Panagiotakos. Successful aging, dietary habits and health status of elderly individuals: A k-dimensional approach within the multi-national MEDIS study. Exp Gerontol. 2014; 60:57-63.


I. Tsiligianni, P. Papadokostakis, D. Prokopiadou, I. Stefanaki, N. Tsakountakis, C. Lionis. Impact of the financial crisis on adherence to treatment of a rural population in Crete, Greece. Quality in Primary Care. 2014; 22 (5): 238-44.




280. C. Napoli, M. Fabbiani, C. Rizzo, M. Barral, J. Oxford, J.M. Cohen, L. Niddam, P. Gorynski, A. Pistol, C. Lionis, S. Briand, A.Nicoll, P. Penttinen, C. Gauci, A. Bounekkar, S. Bonnevay, A. Beresniak. Assessment of Human Influenza Pandemic scenarios in Europe. Eurosurveillance. 2015; 20:7.


G. Duijker, A. Bertsias, E.K. Symvoulakis,J. Moschandreas ,N. Malliaraki, S.P. Derdas, G.K. Tsikalas, H.E. Katerinopoulos ,S.A. Pirintsos , G. Sourvinos, E. Castanas, C.Lionis. Reporting effectiveness of an extract of three traditional Cretan herbs on upper respiratory tract infection: Results from a double-blind randomized controlled trial. Journal of Ethnopharmacology. 2015. [Epub ahead of print].


C. Athanasopoulou, S. Suni, H. Hätönen, I. Apostolakis, C. Lionis, M. Välimäki. Attitudes towards schizophrenia on YouTube: a content analysis of Finnish and Greek videos. Inform Health Soc Care. 2015. 24:1-18. [Epub ahead of print].


C. Lionis. Obituary: Dimitrios Trichopoulos (1938–2014). Journal of Compassionate Health Care. 2015. 2:1.


H.C Maltezou, C. Lionis. The financial crisis and the expected effects on vaccinations in Europe: a literature review. Infectious Diseases. 2015. Early online: 1-10.


285. C. Lionis. Publishing with impact factor- a blessing or a curse? Puls Uczelni. 2015. 9:1. download


Tomas de Brún, Mary O’Reilly de-Brún, Evelyn van Weel-Baumgarten, Maria van den Muijsenbergh, Chris van Weelb, Christopher Dowrick, Christos Lionis, Catherine A O’ Donnell, Nicola Burns, Frances S Mair, Aristoula Saridaki, Maria Papadakaki, Christine Princz, Anne MacFarlane. Guidelines and training initiatives that support communication in cross-cultural primary-care settings: appraising their implementability using Normalization Process Theory. Family Practice, 2015, 1–6.


S. Tyrovolas, JM. Haro, A. Mariolis, S. Piscopo, G. Valacchi, K. Makri, A. Zeimbekis, D. Tyrovola, V. Bountziouka, E. Gotsis, G. Metallinos, JA. Tur, A. Matalas, C. Lionis, E. Polychronopoulos, D. Panagiotakos. The Role of Energy Balance in Successful Aging Among Elderly Individuals: The Multinational MEDIS Study. J Aging Health. 2015 Apr 22. [Epub ahead of print].


O. Kostopoulou, C. Lionis, A. Angelaki, S. Ayis, S. Durbaba, BC. Delaney. Early diagnostic suggestions improve accuracy of family physicians: a randomized controlled trial in Greece. Fam Pract. 2015 ;32(3):323-8


G. Moschonis, K. Tsoutsoulopoulos, E. Efstathopoulou, L. Tsirigoti, CP. Lambrinou, A. Georgiou , C. Filippou , I. Lidoriki , K. Reppas, O. Androutsos, C. Lionis, GP. Chrousos, Y. Manios. Conceptual framework of a simplified multi-dimensional model presenting the environmental and personal determinants of cardiometabolic risk behaviors in childhood. Expert Rev Cardiovasc Ther. 2015;13(6):673-92.


290. Z. Klemenc-Ketis, D. Kurpas, I. Tsiligianni, F. Petrazzuoli, JP. Jacquet, N. Buono, J. Lopez-Abuin, C. Lionis. Is a practice-based rural research network feasible in Europe? Eur J Gen Pract. 2015 Jul


C. Lionis. Why and how is compassion necessary to provide good quality healthcare? Comments from an academic physician. IJHPM. 2015; 4(x): 1-2.


MC. Portillo, E. Regaira, MJ. Pumar-Méndez, A. Mujika, I. Vassilev, A. Rogers, M. Wensing, C. Foss, IR. Knutsen, E. Todorova, P. Roukova, A. Kennedy, M. Serrano, C. Lionis, A. Angelaki, E. Patelarou, J. Koetsenruijter. Voluntary Organizations and Community Groups as New Partners in Diabetes Self-management and Education: A Critical Interpretative Synthesis. Diabetes Educ. 2015 [Epub ahead of print].


A. Rogers, I. Vassilev, MJ. Pumar, E. Todorova, MC. Portillo, C. Foss, J. Koetsenruijter, N. Ratsika, M. Serrano, IA. Knutsen, M. Wensing, P. Roukova, E. Patelarou, A. Kennedy, C. Lionis. Meso level influences on long term condition self-management: stakeholder accounts of commonalities and differences across six European countries. BMC Public Health. 2015; 15: 622.


D. Anyfantakis, EK. Symvoulakis, M. Linardakis, S. Shea, D. Panagiotakos, C. Lionis. Effect of religiosity/spirituality and sense of coherence on depression within a rural population in Greece: the Spili III project. BMC Psychiatry. 2015;15: 173.


C. Lionis. Is there any room for General Practice in Greece? A proposal to scientific and academic stakeholders. Hippokratia. 2014; 18(4):383.


296. V. Tsiantou, J. Moschandreas, A. Bertsias, M. Papadakaki, A. Saridaki, D. Agius, Z. Alper, T. Faresjo, M. Klimkova, L. Martinez, G. Samoutis, J. Vlček, C. Lionis. General practitioners' intention to prescribe and prescribing patterns in selected European settings: The OTCSOCIOMED project. Health Policy. 2015 [Epub ahead of print].


297. C. Lionis. Financial crisis and primary health care in Greece; is it time for family medicine? Family Medicine & Primary Care Review 2015; 17(3): 225–227


298. Y. Adler, P. Charron, M. Imazio, L. Badano, G. Baro n-Esquivias, J. Bogaert, A. Brucato, P. Gueret, K. Klingel, C. Lionis, B. Maisch, B. Mayosi, A. Pavie, P, A. Ristic, M. Sabate Tenas, P. Seferovic, K. Swedberg, W. Tomkowski. 2015 ESC Guidelines for the diagnosis and management of pericardial diseases. European Hert Journal doi:10.1093/eurheartj/ehv318


299. C. Lionis. Evidence-based innovative therapeutic medicine of Cretan plants: some encouraging specific functions and claims. Hell J Nucl Med. 2015;18 (1):145


300. K. Koutra, S. Triliva, T. Roumeliotaki, M. Basta, C. Lionis, AN. Vgontzas. Family Functioning in First-Episode and Chronic Psychosis: The Role of Patient's Symptom Severity and Psychosocial Functioning. Community Ment Health J. 2015 Aug 19. [Epub ahead of print]


301. J. Koetsenruijter, J. van Lieshout, C. Lionis, MC. Portillo, I. Vassilev, E. Todorova, C. Foss, MS. Gil, IR. Knutsen, A. Angelaki, A. Mujika, P. Roukova, A. Kennedy, A. Rogers, M. Wensing. Social Support and Health in Diabetes Patients: An Observational Study in Six European Countries in an Era of Austerity. PLoS One. 2015 Aug 25;10(8):e0135079


302. K. Koutra, S. Triliva, T. Roumeliotaki, M. Basta, P. Simos, C. Lionis, AN. Vgontzas. Impaired family functioning in psychosis and its relevance to relapse: a two-year follow-up study. Compr Psychiatry. 2015; 62:1-12.


303. C. Foss, I. Knutsen, A. Kennedy, E. Todorova, M. Wensing, C. Lionis, MC. Portillo, M. Serrano-Gil, J. Koetsenruijter, A. Mujika, A. Rogers. Connectivity, contest and the ties of self-management support for type 2 diabetes: a meta-synthesis of qualitative literature. Health Soc Care Community. 2015 Oct 1. doi: 10.1111/hsc.12272.


304. V. Sapouna, V. Dafermos, V. Vivilaki, M. Chatziarsenis, I. L. Aivaliotis, P. Bitsios, C.Lionis. Exploring the Burden of the Family Caregivers of Patients with Major Mental Disorders in Greece. REVIEW CLINICAL PHARMACOLOGY AND PHARMACOKINETICS, 2015; 29: 25-35


305. A. Tsiachristas, C. Lionis, J. Yfantopoulos. Bridging knowledge to develop an action plan for integrated care for chronic diseases in Greece. International Journal of Integrated Care. 2015; 15.


306. IR. Knutse, IC. Foss, E. Todorova, P. Roukova, A. Kennedy, MC. Portillo, E. Regaira, M. Serrano-Gil, C. Lionis, A. Angelaki, A. Rogers. Negotiating Diet in Networks: A Cross-European Study of the Experiences of Managing Type 2 Diabetes. Qual Health Res. 2015 Oct 28.


307. Galiè N, Humbert M, Vachiery JL, Gibbs S, Lang I, Torbicki A, Simonneau G, Peacock A, Vonk Noordegraaf A, Beghetti M, Ghofrani A, Gomez Sanchez MA, Hansmann G, Klepetko W, Lancellotti P, Matucci M, McDonagh T, Pierard LA, Trindade PT, Zompatori M, Hoeper M, Aboyans V, Vaz Carneiro A, Achenbach S, Agewall S, Allanore Y, Asteggiano R, Paolo Badano L, Albert Barberà J, Bouvaist H, Bueno H, Byrne RA, Carerj S, Castro G, Erol Ç, Falk V, Funck-Brentano C, Gorenflo M, Granton J, Iung B, Kiely DG, Kirchhof P, Kjellstrom B, Landmesser U, Lekakis J, Lionis C, Lip GY, Orfanos SE, Park MH, Piepoli MF, Ponikowski P, Revel MP, Rigau D, Rosenkranz S, Völler H, Luis Zamorano J. 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT). Eur Heart J. 2016 ;37(1):67-119.




308. A. Tatsioni, C. Lionis. Responding to financial and economic crisis: what methodology and interventions we need in family practice research. Fam Pract. 2016; 33(1):1-3


309. E. Teunissen, A. Tsaparas, A. Saridaki, M. Trigoni, E. van Weel-Baumgarten, C. van Weel, M. van den Muijsenbergh, C. Lionis. Reporting mental health problems of undocumented migrants in Greece: A qualitative exploration. EGJP. 2016; 1381-4788


310. S. Tyrovolas, E. Polychronopoulos, A. Mariolis, S. Piscopo, G. Valacchi, K. Makri, A. Zeimbekis, D. Tyrovolas, V.Bountziouka, E. Gotsis2 , G. Metallinos, J. A. Tur, A. Matalas, C. Lionis, J.M. Haro1 , D.Panagiotakos. Is parental longevity associated with the cardiovascular risk and the successful ageing of their offspring? Results from the multinational MEDIS study. Angiology 2016


311. C. Lionis, E. Petelos. Developing and submitting a proposal for funding in the field of healthcare research or capacity building in response to a call for proposals published by the European Commission: Lessons learned and experiences gained by the research group of Clinic of Social and Family Medicine of the School of Medicine at the University of Crete in Greece. Puls Uczelni 2016 (10) 1.


312. MJ. Pumar-Méndez, A. Mujika, E. Regaira, I. Vassilev, MC. Portillo, C. Foss, E. Todorova, P. Roukova, IA. Ruud Knutsen, M. Serrano, C. Lionis, M. Wensing, A. Rogers. Stakeholders in support systems for self-care for chronic illness: the gap between expectations and reality regarding their identity, roles and relationships. Health Expect. 2016 May 27. doi: 10.1111/hex.12471. [Epub ahead of print]


S. Tyrovolas, JM. Haro , A. Mariolis, S. Piscopo, G. Valacchi, V. Bountziouka, F. Anastasiou, A. Zeimbekis, D. Tyrovola, A. Foscolou, E. Gotsis, G. Metallinos, JA. Tur, A. Matalas, C. Lionis, E. Polychronopoulos, D. Panagiotakos. Skeletal muscle mass and body fat in relation to successful ageing of older adults: The multi-national MEDIS study. Arch Gerontol Geriatr. 2016; 66:95-101.


314. C. O’Donnell, N. Burns , F. Mair, C. Dowrick, C. Clissmann, M. van den Muijsenbergh, E. van Weel-Baumgarten, C. Lionis, M. Papadakaki , A. Saridaki, T. de Brun, A. MacFarlane, on behalf of the RESTORE Team. Reducing the health care burden for marginalised migrants: The potential role for primary care in Europe. Health Policy. 2016; 120(5):495-508


315. C. Athanasopoulou, S. Suni, H. Hätönen, I. Apostolakis, C. Lionis, M. Välimäki. Attitudes towards schizophrenia on YouTube: A content analysis of Finnish and Greek videos. Informatics for Health and Social Care 2016; 41(3):307-24


316. K. Koutra, P. Simos, S. Triliva, C. Lionis, AN. Vgontzas. Linking family cohesion and flexibility with expressed emotion, family burden and psychological distress in caregivers of patients with psychosis: A path analytic model. Psychiatry Res. 2016; 240:66-75.


317. K. Karatzi, G. Moschonis, MC. Polychronopoulou, GP. Chrousos, C. Lionis, Y. Manios; Healthy Growth Study group. Cutoff points of waist circumference and trunk and visceral fat for identifying children with elevated inflammation markers and adipokines: The Healthy Growth Study. Nutrition. 2016; pii: S0899-9007(16)00124-6


318. F. Anastasiou, M. Antonopoulou, I. Tsiligianni, C. Lionis. Long term impact of the economic crisis on health care in the Greek setting: The Pandora box? Health Policy. 2016; pii: S0168-8510(16)30124-5.


319. A. Mariolis, A. Foscolou, S. Tyrovolas, S. Piscopo, G. Valacchi, N. Tsakountakis, A. Zeimbekis, V. Bountziouka, E. Gotsis, G. Metallinos, D. Tyrovola, JA. Tur, AL. Matalas, C. Lionis, E. Polychronopoulos, D. Panagiotakos; MEDIS study group. Successful Aging among Elders Living in the Mani Continental Region vs. Insular Areas of the Mediterranean: the MEDIS Study. Aging Dis. 2016; 7(3):285-94.


320. S. Bellos, P. Skapinakis, D. Rai, P. Zitko, R. Araya, G. Lewis, C. Lionis, V. Mavreas. Longitudinal association between different levels of alcohol consumption and a new onset of depression and generalized anxiety disorder: Results from an international study in primary care. Psychiatry Res. 2016; 243:30-34.


321. C. Girvalaki, S. Papadakis, C. Vardavas, A. Pipe, Christos Lionis. Tobacco treaetment TrAining Network in Crete (TiTAN- Crete): protocol for a controlled before-after study. Tobacco Pevention and Cessation.


322. C. Lionis, M. Papadakaki, A. Saridaki, C. Dowrick, CA. O'Donnell, FS. Mair, M. van den Muijsenbergh, N. Burns, T. de Brún, M. O'Reilly de Brún, Ε. van Weel-Baumgarten, W. Spiegel, A. MacFarlane. Engaging migrants and other stakeholders to improve communication in cross-cultural consultation in primary care: a theoretically informed participatory study. BMJ Open. 2016; 6(7):e010822.


323. D. Sifaki-Pistolla, G. Pistolla, C. Lionis. Re: How should we define health? BMJ 2011; 343:d4163.


324. N. Galiè, M. Humbert, JL. Vachiery, S. Gibbs, I. Lang, A. Torbicki, G. Simonneau, A. Peacock, A. Vonk Noordegraaf, M. Beghetti, A. Ghofrani, MA. Gomez Sanchez, G. Hansmann, W. Klepetko, P. Lancellotti, M. Matucci, T. McDonagh, LA. Pierard, PT. Trindade, M. Zompatori, M. Hoeper, V. Aboyans, A. Vaz Carneiro, S. Achenbach, S. Agewall, Y. Allanore, R. Asteggiano, L. Paolo Badano, J. Albert Barberà, H. Bouvaist, H. Bueno, RA. Byrne, S. Carerj, G. Castro, Ç. Erol, V. Falk, C. Funck-Brentano, M. Gorenflo, J. Granton, B. Iung, DG. Kiely, P. Kirchhof, B. Kjellstrom, U. Landmesser, J. Lekakis, C. Lionis, GY. Lip, SE. Orfanos, MH. Park, MF. Piepoli, P. Ponikowski, MP. Revel, D. Rigau, S. Rosenkranz, H. Völler, J. Luis Zamorano. 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT). European Heart Journal. 2016; 37(1):67-119.


325.AL. Catapano, I. Graham, G. De Backer, O. Wiklund, MJ. Chapman, H. Drexel, AW. Hoes, CS. Jennings, U. Landmesser, TR. Pedersen, Ž. Reiner, G. Riccardi, MR. Taskinen, L. Tokgozoglu, WM. Verschuren, C. Vlachopoulos, DA. Wood, JL. Zamorano; Authors/Task Force Members; Additional Contributor. 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias: The Task Force for the Management of Dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS)Developed with the special contribution of the European Assocciation for Cardiovascular Prevention & Rehabilitation (EACPR). European heart journal 2016; [Epub ahead of print]. 


326. 1.VG. Vivilaki, V. Dafermos, E. Patelarou, D. Bick, A. Syngelaki, ND. Tsopelas, P. Bitsios, ET. Petridou, AN. Vgontzas, C. Lionis. Maternal screening for early postnatal vulnerability. Psychiatriki. 2016;27(3):169-181.


327. 1.S. Shea, G. Samoutis, R. Wynyard, A. Samoutis, C. Lionis, A. Anastasiou, A. Araujo, A. Papageorgiou,  R. Papadopoulos. Encouraging compassion through teaching and learning: a case study in Cyprus. Journal of Compassionate Health Care. 2016 3:10


328. 1.J. Koetsenruijter, N. van Eikelenboom, J. van Lieshout, I. Vassilev, C. Lionis, E. Todorova, M. C. Portillo, C. Foss, M. Serrano Gil, P. Roukova, A. Angelaki, A. Mujika, I. R. Knutsen, A. Rogers, M. Wensing. Social support and self-management capabilities in diabetes patients: An international observational study. Patient Educ Couns. 2016; 99(4):638-43.






329 G. Moschonis, AC. Kaliora, K. Karatzi, A. Michaletos, CP. Lambrinou, AK. Karachaliou, GP. Chrousos, C. Lionis, Y. Manios. Perinatal, sociodemographic and lifestyle correlates of increased total and visceral fat mass levels in schoolchildren in Greece: the Healthy Growth Study. Public Health Nutr. 2017;20(4):660-670.


330 D. Sifaki-Pistolla, C. Lionis, V. Georgoulias, P. Kyriakidis, F. Koinis, S. Aggelaki, N. Tzanakis. Lung cancer and tobacco smoking in Crete, Greece: reflections from a population-based cancer registry from 1992 to 2013. Tob Induc Dis. 2017;15:6.


331K. Karatzi, AD. Protogerou, G. Moschonis, C. Tsirimiagou, O. Androutsos, GP. Chrousos, C. Lionis, Y. Manios. Prevalence of hypertension and hypertension phenotypes by age and gender among schoolchildren in Greece: The Healthy Growth Study. Atherosclerosis. 2017. pii: S0021-9150(17)30029-1.


332 A. Foscolou, S. Tyrovolas, G. Soulis, A. Mariolis, S. Piscopo, G. Valacchi, F. Anastasiou, C. Lionis, A. Zeimbekis, JA. Tur, V. Bountziouka, D. Tyrovola, E. Gotsis, G. Metallinos, AL. Matalas, E. Polychronopoulos, L. Sidossis, DB. Panagiotakos. The Impact of the Financial Crisis on Lifestyle Health Determinants Among Older Adults Living in the Mediterranean Region: The Multinational MEDIS Study (2005-2015). J Prev Med Public Health. 2017;50(1):1-9.


333 S. Tyrovolas, E. Polychronopoulos, M. Morena, A. Mariolis, S. Piscopo, G. Valacchi, V. Bountziouka, F. Anastasiou, A. Zeimbekis, D. Tyrovola, A. Foscolou, E. Gotsis, G. Metallinos, G. Soulis, JA. Tur, A. Matalas, C. Lionis, LS. Sidossis, D. Panagiotakos. Is car use related with successful aging of older adults? Results from the multinational Mediterranean islands study. Ann Epidemiol. 2017;27(3):225-229


334 E. Teunissen, K. Gravenhorst, C. Dowrick, E. Van Weel-Baumgarten, F. Van den Driessen Mareeuw, T. de Brún, N. Burns, C. Lionis, FS. Mair, C. O'Donnell, M. O'Reilly-de Brún, M. Papadakaki, A. Saridaki, W. Spiegel, C. Van Weel, M. Van den Muijsenbergh, A. MacFarlane. Implementing guidelines and training initiatives to improve cross-cultural communication in primary care consultations: a qualitative participatory European study. Int J Equity Health. 2017;16(1):32


335 MC. Portillo, A. Kennedy, E. Todorova, E. Regaira, M. Wensing, C. Foss, C. Lionis, I. Vassilev, V. Goev, A. Rogers. Interventions and working relationships of voluntary organisations for diabetes self-management: A cross-national study. Int J Nurs Stud. 2017;70:58-70.


336 Z. Tsimtsiou, C. Stavropoulou, N. Papastefanou, C. Lionis. Enhancing clinical communication in dermatologists: a personalized educational intervention. J Dermatolog Treat. 2017:1-17.


337 Y. Manios, K. Karatzi, AD. Protogerou, G. Moschonis, C. Tsirimiagou, O. Androutsos, C. Lionis, GP. Chrousos. Prevalence of childhood hypertension and hypertension phenotypes by weight status and waist circumference: the Healthy Growth Study. Eur J Nutr. 2017. doi: 10.1007/s00394-017-1398-y. [Epub ahead of print]


338 C. Lionis, S. Papadakis, C. Tatsi, A. Bertsias, G. Duijker, P.B. Mekouris, W. Boerma, W. Schäfer and on behalf of the Greek QUALICOPC team. Informing primary care reform in Greece: patient expectations and experiences (the QUALICOPC study). BMC Health Services Research. 2017; 17:255


330 M. Papadakaki, C. Lionis, A. Saridaki, C. Dowrick, T. de Brún, M. O'Reilly-de Brún, CA. O'Donnell, N. Burns, E. van Weel-Baumgarten, M. van den Muijsenbergh, W. Spiegel, A. MacFarlane. Exploring barriers to primary care for migrants in Greece in times of austerity: Perspectives of service providers. Eur J Gen Pract. 2017;23(1):128-134.


340 K. Karatzi, AD. Protogerou, G. Moschonis, C. Tsirimiagou, O. Androutsos, GP. Chrousos, C. Lionis, Y. Manios. Reply to: "Considerations about: "Prevalence of hypertension and hypertension phenotypes by age and gender among schoolchildren in Greece: The Healthy Growth Study"". Atherosclerosis. 2017; doi: 10.1016/j.atherosclerosis.2017.04.006 [Epub ahead of print]. 


341 EN Georgousopoulou, DD Mellor, N Naumovski, E Polychronopoulos, S Tyrovolas, S Piscopo, G Valacchi, F Anastasiou, A Zeimbekis, V Bountziouka, E Gotsis, G Metallinos, D Tyrovola, A Foscolou, JA Tur, AL Matalas, C Lionis, L Sidossis, D Panagiotakos; MEDIS study group. Mediterranean lifestyle and cardiovascular disease prevention. Cardiovasc Diagn Ther. 2017;7(Suppl 1):S39-S47. doi: 10.21037/cdt.2017.03.11.


342 A Foscolou, D Panagiotakos, A Mariolis, S Tyrovolas, N Tsakountakis, A Zeimbekis, V Bountziouka, E Gotsis, G Metallinos, D Tyrovola, AL Matalas, C Lionis, E Polychronopoulos. Comparative study on successful aging between the elderly inhabitants of Mani and those living on the Mediterranean islands: The MEDIS study. Clin Nutr ESPEN. 2016;13:e61-e62. doi: 10.1016/j.clnesp.2016.03.031. Epub 2016 May 20. No abstract available.


343I Varlamis, I Apostolakis, D Sifaki-Pistolla, N Dey, V Georgoulias, C Lionis. Application of data mining techniques and data analysis methods to measure cancer morbidity and mortality data in a regional cancer registry: The case of the island of Crete, Greece. Comput Methods Programs Biomed. 2017;145:73-83. doi: 10.1016/j.cmpb.2017.04.011. Epub 2017 Apr 13.


344E Iatraki, PG Simos, A Bertsias, G Duijker, I Zaganas, C Tziraki, AN Vgontzas, C Lionis; THALIS Primary Health Care Research Team/Network. Cognitive screening tools for primary care settings: examining the 'Test Your Memory' and 'General Practitioner assessment of Cognition' tools in a rural aging population in Greece. Eur J Gen Pract. 2017;23(1):171-178. doi: 10.1080/13814788.2017.1324845.


345D Sifaki-Pistolla, C Lionis, F Koinis, V Georgoulias, N Tzanakis; On behalf of the Cancer Registry of Crete (CRC). Lung cancer and annual mean exposure to outdoor air pollution in Crete, Greece. Eur J Cancer Prev. 2017. doi: 10.1097/CEJ.0000000000000407. [Epub ahead of print]


346C Lionis, P Midlöv. Prevention in the elderly: A necessary priority for general practitioners. Eur J Gen Pract. 2017;23(1):202-207. doi: 10.1080/13814788.2017.1350646.


347CA O'Donnell, FS Mair, C Dowrick, MO Brún, T Brún, N Burns, C Lionis, A Saridaki, M Papadakaki, MVD Muijsenbergh, EV Weel-Baumgarten, K Gravenhorst, L Cooper, C Princz, E Teunissen, FVDD Mareeuw, M Vlahadi, W Spiegel, A MacFarlane. Supporting the use of theory in cross-country health services research: a participatory qualitative approach using Normalisation Process Theory as an example. BMJ Open. 2017;7(8):e014289. doi: 10.1136/bmjopen-2016-014289.


348A Kamekis, A Bertsias, J Moschandreas, E Petelos, M Papadakaki, V Tsiantou, A Saridaki, EK Symvoulakis, K Souliotis, N Papadakis, T Faresjö, A Faresjö, L Martinez, D Agius, Y Uncu, T Sengezer, G Samoutis, J Vlcek, A Abasaeed, B Merkouris, C Lionis. Patients' intention to consume prescribed and non-prescribed medicines: A study based on the theory of planned behaviour in selected European countries. J Clin Pharm Ther. 2017. doi: 10.1111/jcpt.12601. [Epub ahead of print]


349M O'Reilly-de Brún, T de Brún, CA O'Donnell , M Papadakaki, A Saridaki, C Lionis, N Burns, C Dowrick, K Gravenhorst, W Spiegel, C Van Weel, E Van Weel-Baumgarten, M Van den Muijsenbergh, A MacFarlane. Material practices for meaningful engagement: An analysis of participatory learning and action research techniques for data generation and analysis in a health research partnership. Health Expect. 2017. doi: 10.1111/hex.12598. [Epub ahead of print]


350. Athanasopoulou, M. Välimäki, K. Koutra, E. Löttyniemi, A. Bertsias, M. Basta, AN. Vgontzas, C. Lionis. (2017). Internet use, eHealth literacy and attitudes toward computer/internet among people with schizophrenia spectrum disorders: a cross-sectional study in two distant European regions. BMC Medical Informatics and Decision Making, 17:136.


351M.  Anastasaki, A. Bertsias, S. A. Pirintsos, E. Castanas, C. Lionis. Post-market outcome of an extract of traditional Cretan herbs on upper respiratory tract infections: a pragmatic, prospective observational study. BMC Complementary and Alternative Medicine (2017) 17:466 DOI 10.1186/s12906-017-1978-7.


352S. Tyrovolas, JM. Haro, A. Foscolou, D. Tyrovola, A. Mariolis, V. Bountziouka, S. Piscopo, G. Valacchi, F. Anastasiou, E. Gotsis, G. Metallinos, N. Papairakleous, E. Polychronopoulos, AL. Matalas, C. Lionis, A. Zeimbekis, JA. Tur, LS. Sidossis, DB. Panagiotakos; MEDIS Study Group. Anti-Inflammatory Nutrition and Successful Ageing in Elderly Individuals: The Multinational MEDIS Study. Gerontology. 2017 Sep 9. doi: 10.1159/000479065. [Epub ahead of print]



363M. Anastasaki, C. Lionis. Developing Family Pratice Research: Recommendations for young researchers from a resource-limited country. Medical Science Pulse. 2017 11:1



364C. Girvalaki, S. Papadakis, C. Vardavas, E. Petridou, A. Pipe, C. Lionis. Smoking cessation delivery by general practitioners in Crete, Greece. Eur J Public Health. 2017 Nov 13. doi: 10.1093/eurpub/ckx201. [Epub ahead of print]



355D. Sifaki-Pistolla, VE. Chatzea, A. Markaki, K .Kritikos, E. Petelos, C. Lionis. Operational integration in primary health care: patient encounters and workflows. BMC Health Serv Res. 2017;17(1):788.



356EN. Georgousopoulou, N. Naumovski, DD. Mellor, S. Tyrovolas, S. Piscopo, G. Valacchi, N. Tsakountakis, A. Zeimbekis, V. Bountziouka, E. Gotsis, G. Metallinos, D. Tyrovola, J. Kellett, A. Foscolou, JA. Tur, AL. Matalas, C. Lionis, E. Polychronopoulos, L. Sidossis, D. Panagiotakos. Association between Siesta (Daytime Sleep), Dietary Patterns and the Presence of Metabolic Syndrome in Elderly Living in Mediterranean Area (Medis Study): The Moderating Effect of Gender. J Nutr Health Aging. 2017;21(10):1118-1124


357T. de Brún, M. O'Reilly-de Brún, E. Van Weel-Baumgarten, N. Burns, C. Dowrick, C. Lionis, C. O'Donnell, FS. Mair, M. Papadakaki, A. Saridaki, W. Spiegel, C. Van Weel, M. Van den Muijsenbergh, A. MacFarlane. Using Participatory Learning & Action (PLA) research techniques for inter-stakeholder dialogue in primary healthcare: an analysis of stakeholders' experiences. Res Involv Engagem. 2017;3:28. 



358. van Loenen, M. van den Muijsenbergh, M. Hofmeester, C. Dowrick, N. van Ginneken, EA. Mechili, A. Angelaki, D. Ajdukovic, H. Bakic, DR. Pavlic, E. Zelko, K. Hoffmann, E. Jirovsky, ES. Mayrhuber, M. Dückers, T. Mooren, J. Gouweloos-Trines, L. Kolozsvári, I. Rurik, C. Lionis. Primary care for refugees and newly arrived migrants in Europe: a qualitative study on health needs, barriers and wishes. Eur J Public Health. 2017 Dec 12. doi: 10.1093/eurpub/ckx210. [Epub ahead of print]







EA. Mechili, A. Angelaki, E. Petelos, D. Sifaki-Pistolla, VE. Chatzea, C. Dowrick, K. Hoffman, E. Jirovsky, D. Rotar Pavlic, M. Dückers, I. Rurik, M. van den Muijsenbergh, T, van Loenen, D.Ajdukovic, H. Bakic, C. Lionis. Compassionate care provision: an immense need during the refugee crisis: lessons learned from a European capacity-building project. Journal of Compassionate Health Care (2018) 5:2


 Wandell P, de Waard AK, KHolzmann MJ, Gornitzki C, Lionis C, de Wit N, Sondergaard J, Sonderlund AL, Kral N, Seifert B, Korevaar J, Schellevis F, Carlsson AC. Barriers and facilitators among health professionals in primary care to prevention of cardiometabolic diseases: A systematic review. Family Practice (2018)


G. Moschonis, K. Karatzi, O. Androutsos, C. Lionis, GP. Chrousos, Y. Manios. Anthropometric cut-off values identifying Greek children at risk of hypertension: the Healthy Growth Study. J Hum Hypertens. 2018;32(3):190-196.


C. Lionis, E. Petelos, EA. Mechili, D. Sifaki-Pistolla, VE> Chatzea, A. Angelaki, I. Rurik, DR. Pavlic, C. Dowrick, M. Dückers, D. Ajdukovic, H. Bakic, E. Jirovsky, ES. Mayrhuber,  M. van den Muijsenbergh, K. Hoffmann. Assessing refugee healthcare needs in Europe and implementing educational interventions in primary care: a focus on methods. BMC Int Health Hum Rights. 2018;18(1):11.


APS. Hungin, CR. Mitchell, P. Whorwell, C. Mulligan, O. Cole, L. Agréus, P. Fracasso, C. Lionis, J. Mendive, JM. Philippart de Foy, B. Seifert, KA.Wensaas, C. Winchester, N. de Wit; European Society for Primary Care Gastroenterology. Systematic review: probiotics in the management of lower gastrointestinal symptoms - an updated evidence-based international consensus. Aliment Pharmacol Ther. 2018


G. Tsirimiagkou, K. Karatzi, AD. Protogerou, G. Moschonis, O. Androutsos, C. Lionis, GP. Chrousos, Y. Manios. Prevalence of childhood hypertension and hypertension phenotypes by weight status and waist circumference: The healthy growth study. Clin Nutr ESPEN. 2018; 24:184.


 I. Chatzakis, K. Vassilakis, C.  Lionis, I. Germanakis. Electronic health record with computerized decision support tools for the purposes of a pediatric cardiovascular heart disease screening program in Crete. Comput Methods Programs Biomed. 2018;159:159-166


AKM de Waard, PE Wandell , MJ Holzmann, JC Korevaar, M Hollander, C Gornitzki, NJ de Wit, FG Schellevis, C Lionis, J Søndergaard, B Seifert, AC Carlsson; on behalf of the SPIMEU Research Group. Barriers and facilitators to participation in a health check for cardiometabolic diseases in primary care: A systematic review. European Journal of Preventive Cardiology 0(00) 1–15.


 C. Girvalaki, S. Papadakis, C. Vardavas, A.L. Pipe, E. Petridou, I. Tsiligianni, C. Lionis; TiTAN Crete Partners. Training General Practitioners in Evidence-Based Tobacco Treatment: An Evaluation of the Tobacco Treatment Training Network in Crete (TiTAN-Crete) Intervention. Health Educ Behav. 2018. [Epub ahead of print]


A.M. de Waard, M. Hollander, J.C. Korevaar, M.M.J. Nielen, A.C. Carlsson, C. Lionis, B. Seifert, T. Thilsing, N.J. de Wit, F.G. Schellevis; SPIMEU Project Group. Selective prevention of cardiometabolic diseases: activities and attitudes of general practitioners across Europe. Eur J Public Health. 2018. [Epub ahead of print]


C. Lionis, G. Dumitra, D. Kurpas, I. Tsiligianni, S. Papadakis, F. Petrazzuoli; EURIPA. Building research capacity in rural health settings: Barriers, priorities and recommendations for practitioners. Aust J Rural Health. 2018. [Epub ahead of print]


M.F. Masana, J.M. Haro, A. Mariolis, S. Piscopo, G. Valacchi, V. Bountziouka, F. Anastasiou, A. Zeimbekis, D. Tyrovola, E. Gotsis, G. Metallinos, A. Polystipioti, JA. Tur, A.L. Matalas, C. Lionis, E. Polychronopoulos, L.S. Sidossis, S. Tyrovolas, D.B. Panagiotakos. Mediterranean diet and depression among older individuals: The multinational MEDIS study. Exp Gerontol. 2018;110:67-72.


A. Foscolou, E. Magriplis, S. Tyrovolas, G. Soulis, V. Bountziouka, A. Mariolis, S. Piscopo, G. Valacchi, F. Anastasiou, E. Gotsis, G. Metallinos, D. Tyrovola, A. Polystipioti, E. Polychronopoulos, A.L. Matalas, C. Lionis, A. Zeimbekis, J.A. Tur, L.S. Sidossis, D. Panagiotakos; MEDIS Study Group. Lifestyle determinants of healthy ageing in a Mediterranean population: The multinational MEDIS study. Exp Gerontol. 2018;110:35-41. 


N. Peroulis, V.P. Androutsopoulos, G. Notas, S. Koinaki, E. Giakoumaki, A. Spyros, E. Manolopoulou, S. Kargaki, M. Tzardi, E. Moustou, E.G. Stephanou, E. Bakogeorgou, N. Malliaraki, M. Niniraki, C. Lionis, E. Castanas, M. Kampa. Significant metabolic improvement by a water extract of olives: animal and human evidence. Eur J Nutr. 2018. [Epub ahead of print]


K. Karatzi, G. Moschonis, S. Botelli, O. Androutsos, G.P. Chrousos, C. Lionis, Y. Manios. Physical activity and sedentary behavior thresholds for identifying childhood hypertension and its phenotypes: The Healthy Growth Study. J Am Soc Hypertens. 2018. [Epub ahead of print]



I. Rurik, L.R. Kolozsvár, D. Aarendonk, A. Angelaki, D. Ajdukovic, C. Dowrick, M. Dückers, K. Hoffmann, Z. Jancsó, E. Jirovsky, Z. Katz, E.A. Mechili, M. van den Muijsenbergh, A. Nánási, E. Petelos, D. Rotar-Pavlic, D. Sifaki-Pistolla, H. Tamás, P. Roland, T. Ungvári, C. Lionis. [Primary care of refugees and migrants. Lesson learnt from the EUR-HUMAN project]. Orv Hetil. 2018;159:1414-1422.


P. Petrou, G. Samoutis, C. Lionis. Single-payer or a multipayer health system: a systematic literature review. Public Health. 2018;163:141-152. 


E. Jirovsky, K. Hoffmann, EA. Mayrhuber, EA. Mechili, A. Angelaki, D. Sifaki-Pistolla, E. Petelos, M. van den Muijsenbergh, T. van Loenen, M. Dückers, LR. Kolozsvári, I. Rurik, D. Rotar Pavlic, DC. Sandoval, G. Borgioli, MJC. Pinilla, D. Ajduković, P. De Graaf, N. van Ginneken, C. Dowrick, C. Lionis. Development and evaluation of a web-based capacity building course in the EUR-HUMAN project to support primary health care professionals in the provision of high-quality care for refugees and migrants. Glob Health Action. 2018;11(1):1547080. 






I.V. Zaganas, P. Simos, M. Basta, S. Kapetanaki, S. Panagiotakis S, I. Koutentaki, N. Fountoulakis, A. Bertsias, G. Duijker, C. Tziraki, N. Scarmeas, A. Plaitakis, D. Boumpas, C. Lionis, A.N. Vgontzas. The Cretan Aging Cohort: Cohort Description and Burden of Dementia and Mild Cognitive Impairment. Am J Alzheimers Dis Other Demen. 2019;34(1):23-33.


C. Lionis, M. Anastasaki. Family Practice Research in low-resource settings: what we have missed and what we have to know. Fam Pract. 2019  23;36(3):253-254.


 Y. Manios, K. Karatzi, G. Moschonis, G. Ioannou, O. Androutsos, C. Lionis, G. Chrousos. Lifestyle, anthropometric, socio-demographic and perinatal correlates of early adolescence hypertension: The Healthy Growth Study.Nutr Metab Cardiovasc Dis. 2019;29(2):159-169


EA. Brakema, FA. van Gemert, RMJJ. van der Kleij, S. Salvi, M. Puhan,NH.  Chavannes; FRESH AIR collaborators. COPD's early origins in low-and-middle income countries: what are the implications of a false start? NPJ Prim Care Respir Med. 2019  5;29(1):6.


 M. Michou, DB. Panagiotakos, C. Lionis, V. Costarelli. Socioeconomic inequalities in relation to health and nutrition literacy in Greece. Int J Food Sci Nutr. 2019 Apr 1:1-7.


 M. Basta, P. Simos, A. Vgontzas, E. Koutentaki, S. Tziraki, I. Zaganas, S. Panagiotakis, S. Kapetanaki, N. Fountoulakis, C. Lionis. Associations between sleep duration and cognitive impairment in mild cognitive impairment.J Sleep Res. 2019 21:e12864.


A. Beresniak, C. Rizzo, J. Oxford, P. Goryński, A. Pistol, M. Fabiani, C. Napoli, M. Barral, L. Niddam, A. Bounekkar, S. Bonnevay, C. Lionis, C. Gauci, D. Bremond. Cost-effectiveness of public health interventions against human influenza pandemics in France: a methodological contribution from the FLURESP European Commission project. Eur J Public Health. 2019 May 5. pii: ckz074.


Lionis C, Petelos E, Papadakis S, Tsiligianni I, Anastasaki M, Angelaki A, Bertsias A, Mechili EA, Papadakaki M, Sifaki-Pistolla D, Symvoulakis E. Towards evidence-informed integration of public health and primary health care: experiences from Crete. Public Health Panorama.2019;4:491-735


Papatheodoridis GV, Goulis J, Sypsa V, Lionis C, Manolakopoulos S, Elefsiniotis I, Anagnostou O, Tsoulas C, Hatzakis A, Dalekos GN. Aiming towards hepatitis C virus elimination in Greece. Ann Gastroenterol. 2019 Jul-Aug;32(4):321-329. doi: 10.20524/aog.2019.0375. Epub 2019 Apr 5.


Král N, de Waard AM, Schellevis FG, Korevaar JC, Lionis C, Carlsson AC, Sønderlund AL, Søndergaard J, Larsen LB, Hollander M, Thilsing T, Angelaki A, de Wit NJ, Seifert B. What should selective cardiometabolic prevention programmes in European primary care look like? A consensus-based design by the SPIMEU group. Eur J Gen Pract. 2019 Jul;25(3):101-108. doi: 10.1080/13814788.2019.1641195. Epub 2019 Aug 14.


van Gemert F, de Jong C, Kirenga B, Musinguzi P, Buteme S, Sooronbaev T, Tabyshova A, Emilov B, Mademilov M, Le An P, Quynh NN, Dang TN, Hong LHTC, Chartier R, Brakema EA, van Boven JFM; FRESH AIR. Effects and acceptability of implementing improved cookstoves and heaters to reduce household air pollution: a FRESH AIR study. NPJ Prim Care Respir Med. 2019 Aug 15;29(1):32. doi: 10.1038/s41533-019-0144-8.


Sbarouni V, Symvoulakis EK, Lionis C. Is primary health care in Greece safe from the 'tsunami' crisis? Enferm Clin. 2019 Aug 19. pii: S1130-8621(19)30292-X. doi: 10.1016/j.enfcli.2019.07.008. [Epub ahead of print] English, Spanish. No abstract available.


Sonderlund AL, Thilsing T, Korevaar J, Hollander M, Lionis C, Schellevis F, Wändell P, Carlsson AC, de Waard AK, de Wit N, Seifert B, Angelaki A, Kral N, Sondergaard J. An evidence-based toolbox for the design and implementation of selective-prevention primary-care initiatives targeting cardio-metabolic disease. Prev Med Rep. 2019 Aug 22;16:100979. doi: 10.1016/j.pmedr.2019.100979. eCollection 2019 Dec. Review.


Lionis C, Symvoulakis EK, Markaki A, Petelos E, Papadakis S, Sifaki-Pistolla D, Papadakakis M, Souliotis K, Tziraki C. Integrated people-centred primary health care in Greece: unravelling Ariadne's thread. Prim Health Care Res Dev. 2019 Jul 25;20:e113. doi: 10.1017/S1463423619000446.


Kjærgaard J, Anastasaki M, Stubbe Østergaard M, Isaeva E, Akylbekov A, Nguyen NQ, Reventlow S, Lionis C, Sooronbaev T, Pham LA, Nantanda R, Stout JW, Poulsen A; FRESH AIR Collaborators. Diagnosis and treatment of acute respiratory illness in children under five in primary care in low-, middle-, and high-income countries: A descriptive FRESH AIR study. PLoS One. 2019 Nov 6;14(11):e0221389. doi: 10.1371/journal.pone.0221389. eCollection 2019.


Anastasaki M, Trigoni M, Pantouvaki A, Trouli M, Mavrogianni M, Chavannes N, Pooler J, van Kampen S, Jones R, Lionis C, Tsiligianni I. Establishing a pulmonary rehabilitation programme in primary care in Greece: A FRESH AIR implementation study. Chron Respir Dis. 2019 Jan-Dec;16:1479973119882939. doi: 10.1177/1479973119882939.


Bariotakis M, Georgescu L, Laina D, Oikonomou I, Ntagounakis G, Koufaki MI, Souma M, Choreftakis M, Zormpa OG, Smykal P, Sourvinos G, Lionis C, Castanas E, Karousou R, Pirintsos SA. From wild harvest towards precision agriculture: Use of Ecological Niche Modelling to direct potential cultivation of wild medicinal plants in Crete. Sci Total Environ. 2019 Dec 1;694:133681. doi: 10.1016/j.scitotenv.2019.133681. Epub 2019 Jul 30.


Butler CC, van der Velden AW, Bongard E, Saville BR, Holmes J, Coenen S, Cook J, Francis NA, Lewis RJ, Godycki-Cwirko M, Llor C, Chlabicz S, Lionis C, Seifert B, Sundvall PD, Colliers A, Aabenhus R, Bjerrum L, Jonassen Harbin N, Lindbæk M, Glinz D, Bucher HC, Kovács B, Radzeviciene Jurgute R, Touboul Lundgren P, Little P, Murphy AW, De Sutter A, Openshaw P, de Jong MD, Connor JT, Matheeussen V, Ieven M, Goossens H, Verheij TJ. Oseltamivir plus usual care versus usual care for influenza-like illness in primary care: an open-label, pragmatic, randomised controlled trial. Lancet. 2020 Jan 4;395(10217):42-52. doi: 10.1016/S0140-6736(19)32982-4. Epub 2019 Dec 12.


Rapti E, Damigos D, Apostolara P, Roka V, Tzavara C, Lionis C. Patients with chronic pain: evaluating depression and their quality of life in a single center study in Greece. BMC Psychol. 2019 Dec 21;7(1):86. doi: 10.1186/s40359-019-0366-0.


Brakema EA, Tabyshova A, van der Kleij RMJJ, Sooronbaev T, Lionis C, Anastasaki M, An PL, Nguyen LT, Kirenga B, Walusimbi S, Postma MJ, Chavannes NH, van Boven JFM; FRESH AIR collaborators. The socioeconomic burden of chronic lung disease in low-resource settings across the globe - an observational FRESH AIR study. Respir Res. 2019 Dec 21;20(1):291. doi: 10.1186/s12931-019-1255-z.











Greek publications


Χ. Λιονής. Πρωτοβάθμια Φροντίδα Υγείας και Τοπική Αυτοδιοίκηση: Απόψεις-Προτάσεις μετά την ψήφιση του Ν. 1622/86. Πρωτοβάθμια Φροντίδα Υγείας 1986; 1:24-31.


Χ. Λιονής. Ο ρόλος του Κέντρου Υγείας μη Αστικού Τύπου στην οργάνωση Συστήματος Πρώτων βοηθειών σε μαζική καταστροφή: Αναφορά στο Κέντρο Υγείας Σπηλίου. Πρωτοβάθμια Φροντίδα Υγείας 1987; 2:33-9.


Χ. Λιονής. Η συμμετοχική διαδικασία απαραίτητος όρος για το σχεδιασμό- προγραμματισμό των δραστηριοτήτων του Κέντρου Υγείας: Αναφορά στο ρόλο της τοπικής επιτροπής υγείας και στην εμπειρία του Κέντρου Υγείας Σπηλίου. Δημόσια Υγεία 1988; 1:23-8.


Χ. Λιονής, Μ. Ξενικάκης, Τ. Ρωμανίδου, Μ. Μαρκουλάκη, Γ. Χατζηδάκης. Κέντρο Υγείας και παρέμβαση στην Κοινότητα: Η έννοια της ομάδας υγείας και ο ρόλος του επόπτη δημόσιας υγείας-αναφορά στο Κέντρο Υγείας Σπηλίου. Δημόσια Υγεία 1988; 1:14-22.


Χ. Λιονής, Κ. Νικηφοράκης, Λ. Σφακιανάκη, Ι. Κανακάκης. Η εκπαίδευση στην Ελλάδα του γιατρού Γενικής και Κοινωνικής Ιατρικής: Ανάλυση-προτάσεις. Ιατρική 1988; 53:383-8.


Α. Κούτης, Χ. Λιονής, M. Cedervall, A. Isacsson, L. Lindholm, Μ. Φιορέτος. Υπολογισμικό Σύστημα Καταγραφής και Στατιστικής Επεξεργασίας Ιατρικών Ιστορικών στην Πρωτοβάθμια Φροντίδα Υγείας: Ένα Εργαλείο Αξιολόγησης. Επιθεώρηση Υγείας 1990 Μάιος-Ιούνιος; 29-33


Χ. Λιονής, Φ. Πιπέρκου, Α. Κούτης, Σ. Σασαρώλης. Κ. Tσαμανδουράκη, M. Φιορέτος. Δημογραφικά χαρακτηριστικά της περιοχής ευθύνης του Κέντρου Υγείας Σπηλίου. Materia Medica Greca 1991; 18:341-4.


Α. Καφάτος, Ι. Αποστολάκη, Ε. Καντιδάκη, Χ. Λιονής. Συνήθειες διατροφής των παιδιών στο σχολείο. Παιδιατρική 1991; 54:10-25.


Γ. Φραντζεσκάκης και Χ. Λιονής. Η Γενική Εξέταση αίματος στο Κέντρο Υγείας.  Πρωτοβάθμια Φροντίδα Υγείας 1991; 3:91-9.


Α. Κούτης, Χ. Λιονής, Ι. Σοφιανού, Γ. Αλαμάνος, Κ. Τσαμανδουράκη, Μ. Φιορέτος. Η οικολογία των συμπτωμάτων ενός γεωγραφικά καθορισμένου πληθυσμού. MateriaMedicaGreca 1991; 19:509-14.


Α. Κούτης, Χ. Λιονής, Γ. Αλαμάνος, Κ. Τσαμανδουράκη, Σ. Σασαρώλης, Y. Tomson, Μ. Φιορέτος. Ζήτηση και χρήση υπηρεσιών πρωτοβάθμιας περίθαλψης σε ένα Κέντρο Υγείας στην Κρήτη. Materia Medica Greca 1991; 19:515-20.


Χ. Λιονής, Γ. Φραντζεσκάκης, Σ. Σασαρώλης, Μ. Μπαθιανάκη. Η Γενική Εξέταση Ούρων στο Κέντρο Υγείας. Πρωτοβάθμια Φροντίδα Υγείας 1992; 4:11-22.


Χ. Λιονής. Γενική Ιατρική – Στρατηγικές Ανάπτυξης. Πρωτοβάθμια Φροντίδα Υγείας 1992; 4:113-4.


Χ. Λιονής και Α. Κούτης. Πρόταση ανάπτυξης του Ελληνικού Κέντρου Υγείας: Η εμπειρία από το Κέντρο Υγείας Σπηλίου. Ιατρική 1992; 62: 392-7.


Χ. Λιονής, Α. Καφάτος, Ι. Βλαχονικολής. Εκπαιδευτική παρέμβαση σε μαθητές Γυμνασίων στην Κρήτη για την πρόληψη των χρόνιων νοσημάτων: Η επίδραση στις γνώσεις. Παιδιατρική 1992; 55:339-51.


Χ. Λιονής, Ν. Αντωνάκης, Α. Κούτης, Κ. Τσαμανδουράκη, Γ. Αλαμάνος, Μ. Τσακαλάκη, Μ. Φιορέτος. Δείκτες θνησιμότητας στην επαρχία Αγίου Βασιλείου Νομού Ρεθύμνου: Στοιχεία του 1989. Ιατρική 1993; 63:158-62.


Χ. Λιονής, Α. Μπένος. Έρευνα και αναπτυξιακή εργασία στη Γενική Ιατρική και στην Πρωτοβάθμια Φροντίδα Υγείας στην Ελλάδα: Μια σημαντική προτεραιότητα. Πρωτοβάθμια Φροντίδα Υγείας 1993; 5:65-7.


Γ. Αλαμάνος, Κ. Τσαμανδουράκη, Α. Κούτης, Χ. Λιονής, Μ. Φιορέτος. Μελέτη των επιπέδων των λιπιδίων και του σακχάρου αίματος, της αρτηριακής πίεσης και του δείκτη μάζας σώματος στο γυναικείο πληθυσμό ενός ορεινού δήμου της Κρήτης. Αρχεία Ελληνικής Ιατρικής 1993; 10:167-70.


Χ. Λιονής. Σχέση Γιατρού-Ασθενούς και Γενική Ιατρική. Πρωτοβάθμια Φροντίδα Υγείας 1993;5:186-8.


Χ. Λιονής, J. L. Slikkerveer, Ν. Φασατάκης, Μ. Φιορέτος. Ονομασίες ασθενειών στην τοπική διάλεκτο της Δυτικής Κρήτης. Το Βήμα των Κοινωνικών Επιστημών 1994; 4:157-71.


Ν. Αντωνάκης, Χ. Λιονής, Α. Κούτης, Μ. Χριστοδουλάκη, Μ. Φιορέτος. Ο Γενικός Γιατρός και η φυσικοθεραπεία του ημιπληγικού, παραπληγικού και τετραπληγικού στο σπίτι. Πρωτοβάθμια Φροντίδα Υγείας 1994; 6:32-40.


Χ. Δ. Λιονής, Α. Κούτης, Φ. Αναστασίου, Ι. Βλαχάκης, Α. Δημητρακάκη, Γ. Μιχαλόπουλος, Ε. Ναθαναηλίδης, Γ. Νότας, Δ. Παπαδημητριάδης, Ν. Σαρουλάκης, Μ. Φιορέτος. Νέες εκπαιδευτικές μέθοδοι για τη σχέση γιατρού-ασθενούς στην προπτυχιακή ιατρική εκπαίδευση. Πρωτοβάθμια Φροντίδα Υγείας 1994; 6:93-6. (Βραβευθείσα ανακοίνωση).


Μ. Φιορέτος, Θ. Διαμαντόπουλος, Μ. Σαββάκη, Χ. Λιονής. Πρωτοβάθμια Φροντίδα Υγείας στην Ελλάδα: Σημερινή κατάσταση και προϋποθέσεις μελλοντικής ανάπτυξης. Πρωτοβάθμια Φροντίδα Υγείας 1994; 6:131-8.


Α. Μπένος, Χ. Λιονής. Η Εκπαίδευση στην Ειδικότητα της Γενικής Ιατρικής: Σχόλια στο νέο Προεδρικό Διάταγμα. Πρωτοβάθμια Φροντίδα Υγείας 1995; 7:14-5.


Α. Φιλαλήθης, Χ. Λιονής, Μ. Φιορέτος. Προτάσεις για την Εκπαίδευση στην Ειδικότητα της γενικής Ιατρικής με βάση το Προεδρικό Διάταγμα 415/1994. Πρωτοβάθμια Φροντίδα Υγείας 1995; 7:43-52.


Χ. Λιονής, Θ. Σηφάκη, Α. Κούτης, Μ. Βολουδάκη, Μ. Βιτσαξάκη, Ε. Πεδιαδίτη, Μ. Φιορέτος. Εκτίμηση των Αναγκών σε Εμβολιασμούς Παιδιών Προσχολικής και Σχολικής Ηλικίας στο Δήμο Αρχανών. Πρωτοβάθμια Φροντίδα Υγείας 1995; 7:96-100. (Βραβευθείσα ανακοίνωση).


Α. Κούτης, Χ. Λιονής, Ν. Αντωνάκης, Σ. Σασαρώλης, Γ. Φραντζεσκάκης, Μ. Φιορέτος. Εκτίμηση επιπολασμού σακχαρώδη διαβήτη και αρτηριακής υπέρτασης σ’ ένα γεωγραφικά καθορισμένο πληθυσμό. Ιατρική 1995; 68:53-8.


Χ. Λιονής, Α. Κούτης. Εκτίμηση των προβλημάτων υγείας στην κοινότητα: ο ρόλος του γενικού γιατρού. Ιατρική 1995; 68:570-5.


Χ. Λιονής, Μ. Μπαθιανάκη, Ι. Μοσχανδρέα, Ι. Βλαχονικολής, Μ. Φιορέτος. Πρωτοβάθμια Φροντίδα και Ιατρείο Διαλογής σε Περιφερειακό Νοσοκομείο: Ο ρόλος της Γενικής/Οικογενειακής Ιατρικής. Πρωτοβάθμια Φροντίδα Υγείας 1996; 8:77-86. (Βραβευθείσα εργασία στο διαγωνισμό εις μνήμη Καθ. Δ. Ικκου).


Τ. Ρωμανίδου, Ι. Γιωτάκη, Ν. Καρπέτα, Γ. Φραντζεσκάκης, Σ. Σασαρώλης, Χ. Λιονής. Ανάλυση των παθολογικών εξετασθέντων κατά Παπανικολάου τραχηλικών επιχρισμάτων στις γυναίκες της επαρχίας Αγίου Βασιλείου τα έτη 1993 και 1994 και έλεγχος της συμμόρφωσης στις συστάσεις του υγειονομικού προσωπικού. Πρωτοβάθμια Φροντίδα Υγείας 1996; 8:97-105. (Βραβευθείσα ανακοίνωση)


Χ. Λιονής, Α. Συμεωνίδης. Σχέση Γιατρού-Ασθενούς: πρώτη προτεραιότητα για εκπαίδευση και έρευνα στη Γενική/ Οικογενειακή Ιατρική. Πρωτοβάθμια Φροντίδα Υγείας 1996; 9:16-7. (Της Σύνταξης)


Σ. Αργυριάδου, Α. Μπένος, Χ. Λιονής. Άνοια και κατάθλιψη στην τρίτη ηλικία: Η κατάσταση στην Ελλάδα σήμερα και ο ρόλος του Γιατρού Γενικής/Οικογενειακής Ιατρικής. Πρωτοβάθμια Φροντίδα Υγείας 1997; 8:203-12.


Θ. Ευαγγελίου, Χ. Λιονής, Μ. Σπηλιώτη, Σ. Κουτράκη, Π. Νικητάκης, Γ. Φραντζεσκάκης, Σ. Σασαρώλης, Ν. Παπαδάκης, Α. Τσικαλά, Ο. Κόπολα-Σιτορένγκο, Μ. Χατζηαρσένης, Μ. Βιτσαξάκη, Ε. Πεδιαδίτη, Σ. Σμπυράκης. Η συμβολή και ο ρόλος της Γενικής Ιατρικής και της Πρωτοβάθμιας Φροντίδας Υγείας στην έγκαιρη διάγνωση των νευροεκφυλιστικών μεταβολικών νοσημάτων στην παιδική ηλικία. Πρωτοβάθμια Φροντίδα Υγείας 1997; 9:79-87. (Βραβευθείσα εργασία στο διαγωνισμό εις μνήμη Καθ. Δ. Ικκου)


Ν. Αντωνάκης και Χ. Λιονής. Εφαρμογές των ηλεκτρονικών υπολογιστών στην Πρωτοβάθμια Φροντίδα Υγείας και στη Γενική/Οικογενειακή Ιατρική. Πρωτοβάθμια Φροντίδα Υγείας 1997; 9:229-38.


Ν. Αντωνάκης, Κ. Μακρή, Χ. Καλπαδάκη, Χ. Λιονής. Δείκτες θνησιμότητας στον πληθυσμό ενός ορεινού δήμου της Κρήτης. Αρχεία Ελληνικής Ιατρικής 1997; 14:294-9.


Χ. Λιονής, Ε. Στεφάνου. Αλκοόλ, φίλος ή εχθρός; Αρχεία Ελληνικής Ιατρικής 1997; 14:535-41.


Χ. Λιονής. Mαζικός έλεγχος του πληθυσμού για καρκίνο του μαστού: Σχεδιασμός, οργάνωση και αξιολόγηση  προγραμμάτων με βάση τη μαστογραφία. Ελληνική Χειρουργική 1997; 69:513-23


Ν. Αντωνάκης και Χ. Λιονής. Ανάπτυξη ηλεκτρονικής βάσης δεδομένων στο Κέντρο υγείας Ανωγείων Ρεθύμνης. Ιατρική 1998; 74:320-8


Χ. Λιονής. Στην πορεία μιας αλλαγής. Πρωτοβάθμια Φροντίδα Υγείας 1998; 10:8. (Άρθρο Σύνταξης)


Τ. Παναγιωτόπουλος, Ε. Βαλάσση-Αδάμ, Ε. Σαραφίδου, Α. Μανδέκη, Ζ. Στρατίκη, Α. Μπένος, Δ. Αδαμίδης, Α. Κούτης, Χ. Λιονής. Πανελλαδική μελέτη κατάστασης εμβολιασμού. Αρχεία Ελληνικής Ιατρικής 1999; 16:154-62.


Δ. Δρυγιαννάκης, Α. Μπατίκας, Γ. Φραντζεσκάκης, Χ. Σαββάκη, Σ. Σασσαρώλης, Ν. Παπαδάκης, Γ. Αλεξανδράκης, Ι. Δρυγιαννάκης, Χ. Λιονής, Η. Κουρούμαλης. Ανίχνευση αυτοαντισωμάτων (Α.Α.) σε ασθενείας με χρόνια ηπατίτιδα C (HCV). Πρωτοβάθμια Φροντίδα Υγείας 1999; 11:85-91. (Bραβευθείσα εργασία στο διαγωνισμό εις μνήμη Καθ. Δ. Ίκκου)


Χ. Λιονής. Γενική/Οικογενειακή Ιατρική. Μια ανατέλλουσα και πολλά υποσχόμενη ιατρική ειδικότητα. Ιατρική 2000; 77:324-7.(Άρθρο Σύνταξης)


Χ. Λιονής. Ο Ρόλος του Γενικού ιατρού στην Πρωτοβάθμια Φροντίδα Υγείας. Νοσοκομειακά Χρονικά 2000; 62:73-5.


Ν. Αντωνάκης, Ν. Τσακουντάκης, Σ. Τσούλου, Μ. Φιλιππάκη, Χ. Λιονής. Η συνταγογραφία στην Πρωτοβάθμια Φροντίδα Υγείας 1. Τα αντιμικροβιακά. Αρχεία Ελληνικής Ιατρικής 2000; 17:44-51


Ν. Αντωνάκης, Ν. Τσακουντάκης, Χ. Λιονής. Η χρήση της ιατρικής στατιστικής σε επιλεγμένα ιατρικά περιοδικά της Ελλάδας και του εξωτερικού. Ιατρική 2000; 78:61-5.


Κ. Ερευνίδου, Μ. Μυλωνάκης, Ε. Μήττας, Ι. Βλαχονικολής, Χ. Λιονής. Ιατρικές επισκέψεις σε γιατρό Γενικής Ιατρικής μιας τουριστικής περιοχής της Κρήτης στη διάρκεια της νύχτας. Ιατρική 2000; 78:261-5.


Χ. Λιονής, Μ. Π. Μερκούρης. Απόψεις για τη σημερινή κατάσταση στην Πρωτοβάθμια Φροντίδα Υγείας και προτάσεις για την βελτίωσή της. Πρωτοβάθμια Φροντίδα Υγείας 2000; 12:7-9.


Χ. Λιονής και Γ. Κυριόπουλος. Πρωτοβάθμια Φροντίδα Υγείας και Γενική Ιατρική: η ασφαλιστική δικλείδα για την υψηλή ποιότητα στη φροντίδα υγείας. Πρωτοβάθμια Φροντίδα Υγείας 2000; 12:167-8.


Γ. Κυριόπουλος, Χ. Λιονής, Γ. Δημολιάτης, Μ. Π. Μερκούρης, Χ. Οικονόμου, Γ. Τσάκος, Α. Φιλαλήθης και ομάδα εργασίας. Η Πρωτοβάθμια Φροντίδα Υγείας ως θεμέλιο της υγειονομικής μεταρρύθμισης. Πρωτοβάθμια Φροντίδα Υγείας 2000; 12:169-188.


X. Λιονής, Μ. Π. Μερκούρης. Η Γενική / Οικογενειακή Ιατρική σε σταυροδρόμι: Προϋποθέσεις απαραίτητες για την εδραίωση της στην Ελλάδα. Πρωτοβάθμια Φροντίδα Υγείας 2001; 13:8-9. (της Σύνταξης)


Α. Μπατίκας, Ν. Αντωνάκης, Κ. Λιάπης, Ε. Παπουτσιδάκης, Ε. Χαριτάκη, Ν. Παπαδάκης, Α. Καρόκης, Χ. Λιονής. Η επαναλαμβανόμενη συνταγογραφία δείκτης πτωχής (ελλιπούς) ιατρικής φροντίδας: μία πιλοτική μελέτη σε ένα Κέντρο Υγείας της Κρήτης. Πρωτοβάθμια Φροντίδα Υγείας 2001; 13:121-6. (Eπαινεθείσα εργασία στο 13ο Πανελλήνιο Συνέδριο Γενικής Ιατρικής)


Μ. Αντωνοπούλου, C. Ekdahl, Μ. Σγάντζος, Ν. Αντωνάκης, Χ. Λιονής. Μετάφραση και προσαρμογή στην ελληνική γλώσσα ενός σκανδιναβικού ερωτηματολογίου για τα πρωτοβάθμια συμπτώματα από το μυοσκελετικό σύστημα. Πρωτοβάθμια Φροντίδα Υγείας 2001; 13:209-13.


Χ. Λιονής, Α. Τατσιώνη, P. Heuberger, Ε. vanMuijden–Karssen, H. VanderSchaaf  και συν. Κατευθυντήριες οδηγίες στην Πρωτοβάθμια Φροντίδα Υγείας: ένα κείμενο βασισμένο στη συνάντηση εργασίας Ελλήνων και Ολλανδών ερευνητών και γενικών ιατρών. Πρωτοβάθμια Φροντίδα Υγείας 2001; 13:214-21.


Ν. Αντωνάκης, Σ. Τσούλου, Δ. Πέϊος, Π. Συμεωνίδης, Ε. Λυραράκη Χ. Λιονής. Η συνταγογραφία στην Πρωτοβάθμια Φροντίδα Υγείας. ΙΙ. Φάρμακα καρδιαγγειακού, μυοσκελετικού και κεντρικού νευρικού συστήματος. Αρχεία Ελληνικής Ιατρικής 2001; 18:50-7.


Ν. Αντωνάκης, Ν. Πλουμής, Μ. Σαριδάκης, Κ. Μακρή, Μ. Φιλιππάκη,  Χ. Λιονής. Η συνταγογραφία στην Πρωτοβάθμια Φροντίδα Υγείας ΙΙΙ. Η προοπτική μελέτη του Κέντρου Υγείας Ανωγείων. Αρχεία Ελληνικής Ιατρικής 2001; 18:379-88.


Κ. Ανυφαντάκης, Μ. Ανυφαντάκη, Ε. Ξυλούρη, Ε. Σακκά, Χ. Λιονής, Ν. Αντωνάκης. Συμπεριφορά, διατροφή, σωματική υγιεινή, τηλεθέαση και παιχνίδι μαθητών στοιχειώδους εκπαίδευσης στην Κρήτη. Παιδιατρική  2002; 65:186-94.


Χ. Λιονής. Μέτρηση της ποιότητας ζωής στην Πρωτοβάθμια Φροντίδα Υγείας και στην Γενική Ιατρική. Νέα Υγεία 2002; 36:7.


Χ. Λιονής. Το σχέδιο νόμου για την Πρωτοβάθμια Φροντίδα Υγείας - Μια πρόκληση στη Μεταρρύθμιση της Υγείας. Πρωτοβάθμια Φροντίδα Υγείας 2002; 14:11-2.


Η. Μαζοκοπάκης, Χ. Λιονής. Καπνιστικές συνήθειες στο προσωπικό ενός πολεμικού πλοίου. Ιατρική Επιθεώρηση Ενόπλων Δυνάμεων 2002; 36:101-11.


Χ. Λιονής, Ν. Αντωνάκης, Μ. Αντωνοπούλου, Σ. Αργυριάδου, Ε. Γεωργακίλα, Ν. Γεωργιάννος και συν. Βήματα για την ανάπτυξη κατευθυντηρίων οδηγιών στην Γενική Ιατρική στην Ελλάδα: Ένα κείμενο ομοφωνίας. Πρωτοβάθμια Φροντίδα Υγείας 2003; 15:91-3.


X. Λιονής. Κρίση στην Πρωτοβάθμια Φροντίδα Υγείας – Ρητορεία ή πραγματικότητα; Πρωτοβάθμια Φροντίδα Υγείας 2003; 15:8-9. (Άρθρο σύνταξης)


Χ. Λιονής. Συχνότητα των ψυχικών διαταραχών στην Πρωτοβάθμια Φροντίδα Υγείας και ο ρόλος του ιατρού Γενικής/Οικογενειακής Ιατρικής: Εμπειρίες από την Ελλάδα. Ελληνική Ψυχιατρική Γενικού Νοσοκομείου 2003; 1:20-3.


Κ. Σουλιώτης, Χ. Λιονής. Λειτουργική ανασυγκρότηση της Πρωτοβάθμιας Φροντίδας Υγείας. Μια πρόταση για την άρση του αδιεξόδου. Αρχεία Ελληνικής Ιατρικής 2003;20: 466-76.


Ι. Καράλης, Α. Langius, Μ. Τσιρογιάννη, Τ. Faresjö, P. Nettelbladt, Χ. Λιονής. Η μετάφραση–στάθμιση της κλίμακας «αίσθηση συνεκτικότητας» (senseofcoherence) στην Ελλάδα και η χρήση της στην πρωτοβάθμια φροντίδα υγείας. Αρχεία Ελληνικής Ιατρικής 2004; 21:195-203.


Α. Μαριόλης, X. Λιονής. 16ο Πανελλήνιο Συνέδριο Γενικής Ιατρικής: Αφετηρία για μια νέα εποχή στη Γενική Ιατρική; Πρωτοβάθμια Φροντίδα Υγείας 2004; 16:54-5. (Αρθρο Σύνταξης)


X. Λιονής. Η αναζήτηση της διαγνωστικής πιθανότητας, προτεραιότητα για την έρευνα στην Γενική Ιατρική στη χώρα μας. Πρωτοβάθμια Φροντίδα Υγείας 2004; 16:155-6. (Άρθρο σύνταξης)


Ε. Α. Σκληρός, Γ. Γιαννακάκη, Α. Σωτηρόπουλος, Ι. Παπαϊωάννου, Μ. Μάγκου, Μ. Μηλίγκου, Ε. Κτώρου, Σ. Παπαδοδήμα, Χ. Λιονής. Επιδημιολογικά χαρακτηριστικά της υπέρτασης σε ένα γεωγραφικά καθορισμένο πληθυσμό τρίτης ηλικίας. Η μελέτη της Νεμέας. Ιατρική 2004; 85:286-92.


Χ. Λιονής. Ενώπιον διλημμάτων: Η γενική ιατρικη ως παράγων βελτίωσης της κλινικής αποτελεσματικότητας και της ποιότητας στη φροντίδα υγείας. Πρωτοβάθμια Φροντίδα Υγείας 2005; 17:108-9. (Άρθρο σύνταξης)


Χ. Λιονής, Π. Θεοδωράκης, Σ. Αργυριάδου. Ψυχικές διαταραχές και Γενική Ιατρική: Στο επίκεντρο του ενδιαφέροντος. Πρωτοβάθμια Φροντίδα Υγείας 2006; 18:6-7. (Άρθρο σύνταξης)


Χ. Λιονής, Κ. Μάκρη. Τι δημοσιεύεται σε αυτό το τεύχος. Πρωτοβάθμια Φροντίδα Υγείας 2006; 18:66. (Άρθρο σύνταξης)


Ζ. Τσιμτσίου, Σ. Δημοπούλου, Δ. Βασιλοπούλου, Σ. Αργυριάδου, Χ. Λιονής. Σχέση ιατρού – ασθενή και πρωτοβάθμια φροντίδα υγείας: Σκέψεις και παραλληλισμοί με αφορμή την επίσκεψη στο Ιερό Κοινόβιο Ευαγγελισμού της Θεοτόκου στην Ορμύλια Χαλκιδικής. Πρωτοβάθμια Φροντίδα Υγείας 2006; 18:95–7.


B. Σαπουνά, Α. Η. Schene, Β. Δαφέρμος, Π. Θεοδωράκης, Μ. Χατζηαρσένης, Χ. Λιονής. Επιβάρυνση μελών οικογενειών και άλλων ατόμων που φροντίζουν ασθενείς με μείζονες ψυχικές διαταραχές στην Κρήτη: Ένα καινούριο πεδίο για την Γενική Ιατρική στην Ελλάδα. Πρωτοβάθμια Φροντίδα Υγείας 2006; 18:113-24.  (Βραβείο Δ. Ικκου στο 18ο Πανελλήνιο Συνέδριο Γενικής Ιατρικής)


Χ. Λιονής, Α. Μαρκάκη. Οι νοσηλευτές στην Πρωτοβάθμια Φροντίδα Υγείας: αναγκαιότητα ή ουτοπία; Πρωτοβάθμια Φροντίδα Υγείας 2006; 18:164-5. (Άρθρο σύνταξης)


Χ. Λιονής. Υγεία στις αγροτικές περιοχές και γενική ιατρική: ένα γνωστό από παλιά θέμα στην Ελλάδα και μια καινούργια πρόκληση. Πρωτοβάθμια Φροντίδα Υγείας 2007; 19:6-7. (Άρθρο σύνταξης)


Δ. Κουναλάκης, Μ. Π. Μερκούρης, Α. Φιλαλήθης, Χ. Λιονής. Ανάπτυξη, εφαρμογή και αξιολόγηση ηλεκτρονικού φακέλλου ασθενή κατάλληλου για την πρωτοβάθμια φροντίδα υγείας στην Ελλάδα: εμπειρίες από την εκπόνηση μιας διδακτορικής διατριβής στην Κρήτη. Πρωτοβάθμια Φροντίδα Υγείας 2007; 19:20-32. (Επαινεθείσα εργασία στο 18ο Πανελλήνιο Συνέδριο Γενικής Ιατρικής)


Χ. Λιονής, Κ. Μακρή. Τι θα διαβάσετε σ’ αυτό το τεύχος – Μία νέα περίοδος και μία νέα πρόκληση. Πρωτοβάθμια Φροντίδα Υγείας 2007; 19:60. (Άρθρο σύνταξης)


Χ.Λιονής. Παρουσίαση και κριτική ανάλυση της έρευνας σχετικής με την άνοια στην Πρωτοβάθμια Φροντίδα Υγείας. Εγκέφαλος 2007;44:54.


Α. Καφάτος, Χ.Χατζής, Μ. Λιναρδάκης, Δ. Αθανασόπουλος, Χ.Λιονής, Ε. Μπαλωμενάκη, Α. Καπνισάκης, Ε. Σταματάκη.. Παιδιατρική 2007; 70:97–106.


Ε. Θηραίος, E. Trell, Μ. Φιορέτος, Α. Κούτης, Χ. Λιονής. «ΥΓΕΙΟΜΕΤΡΟ»: Ένα εργαλείο αποτίμησης του κινδύνου για την υγεία. Κοινωνία, Οικονομία και Υγεία, Ιούλιος – Δεκέμβριος 2007; 1:107-14.


Χ. Λιονής, Κ. Σουλιώτης. Η αναγκαιότητα για ένα νέο επιστημονικό περιοδικό. Κοινωνία, Οικονομία και Υγεία, Ιούλιος – Δεκέμβριος 2007; 1:3-4. (Άρθρο σύνταξης)


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